ARPC3 Rabbit Polyclonal Antibody

CAT#: TA387976M

ARPC3 Rabbit polyclonal antibody

Size: 50 ug 100 ug



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CNY 1350.00


货期*
2周

规格
    • 50 ug

Product images

Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)
Isotype IgG
Formulation Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration lot specific
Purification >95%, Protein G purified
Conjugation Unconjugated
Storage Condition Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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