LC3B (MAP1LC3B) Rabbit Polyclonal Antibody

CAT#: TA392615S

MAP1LC3B (D23) polyclonal antibody

Size: 25 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 25 ul

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经常一起买 (1)
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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to residues in Human MAP1LC3B.
Specificity MAP1LC3B (D23) polyclonal antibody detects endogenous levels of LC3-I and LC3-II protein.
Formulation Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Condition Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size ~ 16-18 kDa
Gene Name microtubule associated protein 1 light chain 3 beta
Background MAP1LC3B, a homolog of Apg8p, is essential for autophagy and associated to the autophagosome membranes after processing. Two forms of LC3β , the cytosolic LC3-I and the membrane-bound LC3-II, are produced post-translationally. LC3-I is formed by the removal of the C-terminal 22 amino acids from newly synthesized LC3β , followed by the conversion of a fraction of LC3-I into LC3-II. LC3 enhances fibronectin mRNA translation in ductus arteriosus cells through association with 60S ribosomes and binding to an AU-rich element in the 3’ untranslated region of fibronectin mRNA. This facilitates sorting of fibronectin mRNA onto rough endoplasmic reticulum and translation. MAP LC3β may also be involved in formation of autophagosomal vacuoles. It is expressed primarily in heart, testis, brain and skeletal muscle.
Synonyms Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; LC3-I; LC3-II; LC3I; LC3II; MAP1 light chain 3-like protein 2; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1ALC3; MAP1LC3B; Microtubule-associated protein 1 light chain 3 beta; Microtubule-associated proteins 1A/1B light chain 3B
Note For research use only, not for use in diagnostic procedure.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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