Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:500~1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 163-213 of Human AURKB.
Specificity	AURKB/C (K197) polyclonal antibody detects endogenous levels of AURKB and AURKC protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 55, 40, 45 kDa
Database Link	UniProt ID Q96GD4/Q9UQB9
Background	Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among mammals: Aurora A, B, and C. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
Synonyms	AIE2; AIK2; AIK3; AIM-1; AIM1; AIRK2; AIRK3; ARK-2; ARK-3; ARK2; ARK3; AURKB; AURKC; Aurora- and IPL1-like midbody-associated protein 1; Aurora-related kinase 2; Aurora-related kinase 3; Aurora/IPL1-related kinase 2; Aurora/IPL1-related kinase 3; Aurora/IPL1/Eg2 protein 2; Aurora 1; Aurora 3; Aurora kinase B; Aurora kinase C; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-B; Serine/threonine-protein kinase aurora-C; STK-1; STK1; STK5; STK12; STK13
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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