Calreticulin (CALR) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:1000 IHC: 1:50~1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 20-70 of Human Calregulin.
Specificity	Calregulin (G54) polyclonal antibody detects endogenous levels of Calregulin protein
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 60 kDa
Gene Name	calreticulin
Database Link	Entrez Gene 811 Human UniProt ID P27797
Background	Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis
Synonyms	CALR; Calregulin; Calreticulin; CRP55; CRTC; Endoplasmic reticulum resident protein 60; ERp60; grp60; HACBP
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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