MRPL39 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000~1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 296-356 of Human MRphospho-L39.
Specificity	MRphospho-L39 (E326) polyclonal antibody detects endogenous levels of MRphospho-L39 protein.
Isotype	IgG
Formulation	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration	1mg/ml
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Predicted Protein Size	~ 38 kDa
Gene Name	mitochondrial ribosomal protein L39
Database Link	Entrez Gene 54148 Human UniProt ID Q9NYK5
Background	Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRphospho-L39 (mitochondrial ribosomal protein L39), also known as MRphospho-L5, L39mt or L5mt, is a 338 amino acid mitochondrial protein that exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. MRphospho-L39 exists as two isoforms produced by alternative splicing. Isoform one of MRphospho-L39 is ubiquitously expressed while isoform two is specifically expressed in heart. The gene encoding MRphospho-L39 maps to chromosome 21, which makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer’s disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21.
Synonyms	39S ribosomal protein L5, mitochondrial; 39S ribosomal protein L39, mitochondrial; C21orf92; L5mt; L39mt; Mitochondrial large ribosomal subunit protein mL39; MRphospho-L5; MRphospho-L39; MRPL5; MRPL39; MSTP003; PRED22; RPML5
Note	For research use only, not for use in diagnostic procedure.
Reference Data

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