PDE10A Mouse Monoclonal Antibody [Clone ID: OTI3G9]

Specifications

Product Data
Clone Name	OTI3G9
Applications	FC, IF
Recommend Dilution	IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PDE10A (NP_006652) produced in HEK293T cell.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	phosphodiesterase 10A
Database Link	NP_006652 Entrez Gene 63885 RatEntrez Gene 10846 Human UniProt ID Q9Y233
Background	Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]). [supplied by OMIM]
Synonyms	FLJ11894; FLJ25677; HSPDE10A
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Progesterone-mediated oocyte maturation, Purine metabolism

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