Glutamine Synthetase (GLUL) Mouse Monoclonal Antibody [Clone ID: OTI1F4]

Specifications

Product Data
Clone Name	OTI1F4
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:1000~2000, IHC 1:50, IF 1:50~100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human GLUL (NP_002056) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	41.9 kDa
Gene Name	glutamate-ammonia ligase
Database Link	NP_002056 Entrez Gene 14645 MouseEntrez Gene 24957 RatEntrez Gene 2752 Human UniProt ID P15104
Background	The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.
Synonyms	GLNS; GS; PIG43; PIG59
Reference Data
Protein Pathways	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways, Nitrogen metabolism

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