TTL Mouse Monoclonal Antibody [Clone ID: OTI3G5]

Specifications

Product Data
Clone Name	OTI3G5
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TTL (NP_714923) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.42 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	43.0 kDa
Gene Name	tubulin tyrosine ligase
Database Link	NP_714923 Entrez Gene 69737 MouseEntrez Gene 171572 RatEntrez Gene 150465 Human UniProt ID Q8NG68
Background	TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]). [supplied by OMIM]. COMPLETENESS: complete on the 3' end.
Synonyms	MGC46235
Reference Data

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