eRF1 (ETF1) Mouse Monoclonal Antibody [Clone ID: OTI2E3]

Specifications

Product Data
Clone Name	OTI2E3
Applications	FC, WB
Recommend Dilution	WB 1:500, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ETF1 (NP_004721) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.97 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	48.9 kDa
Gene Name	eukaryotic translation termination factor 1
Database Link	NP_004721 Entrez Gene 307503 RatEntrez Gene 2107 Human UniProt ID P62495
Background	This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X. [provided by RefSeq, Jan 2012]
Synonyms	D5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1
Reference Data

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