IRF6 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2C10]

Specifications

Product Data
Clone Name	OTI2C10
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human, Dog, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human IRF6(NP_006138) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52.9 kDa
Gene Name	interferon regulatory factor 6
Database Link	NP_006138 Entrez Gene 54139 MouseEntrez Gene 364081 RatEntrez Gene 480015 DogEntrez Gene 3664 Human UniProt ID O14896
Background	This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
Synonyms	LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
Reference Data
Protein Families	ES Cell Differentiation/IPS, Transcription Factors

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