ALG2 Mouse Monoclonal Antibody [Clone ID: OTI2A3]

Specifications

Product Data
Clone Name	OTI2A3
Applications	IF, IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150, IF 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human ALG2(NP_149078) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.83 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46.9 kDa
Gene Name	ALG2 alpha-1,3/1,6-mannosyltransferase
Database Link	NP_149078 Entrez Gene 56737 MouseEntrez Gene 313231 RatEntrez Gene 85365 Human UniProt ID Q9H553
Background	This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms	CDGIi; hALPG2; NET38
Reference Data
Protein Pathways	Metabolic pathways, N-Glycan biosynthesis

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