RASSF8 Mouse Monoclonal Antibody [Clone ID: OTI1F5]

Specifications

Product Data
Clone Name	OTI1F5
Applications	IHC, WB
Recommend Dilution	WB 1:1000, IHC 1:150
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human RASSF8(NP_009142) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45.3 kDa
Gene Name	Ras association domain family member 8
Database Link	NP_009142 Entrez Gene 71323 MouseEntrez Gene 312846 RatEntrez Gene 11228 Human UniProt ID Q8NHQ8
Background	This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May
Synonyms	C12orf2; HOJ1
Reference Data

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