GGA2 Mouse Monoclonal Antibody [Clone ID: OTI1D2]

Specifications

Product Data
Clone Name	OTI1D2
Applications	WB
Recommend Dilution	WB 1:4000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human GGA2(NP_055859) produced in HEK293T cell
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	67 kDa
Gene Name	golgi associated, gamma adaptin ear containing, ARF binding protein 2
Database Link	NP_055859 Entrez Gene 74105 MouseEntrez Gene 293455 RatEntrez Gene 23062 Human UniProt ID Q9UJY4
Background	This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008]
Synonyms	VEAR
Reference Data
Protein Pathways	Lysosome

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