CD63 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI5E5]

Specifications

Product Data
Clone Name	OTI5E5
Applications	IHC, Simple Western, WB
Recommend Dilution	WB 1:2000, IHC 1:150, Simple Western 1:20-1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human CD63 (NP_001771) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25.5 kDa
Gene Name	CD63 molecule
Database Link	NP_001771 Entrez Gene 967 Human UniProt ID P08962
Background	The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Synonyms	LAMP-3; ME491; MLA1; OMA81H; TSPAN30
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Lysosome

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