Nkx3.1 (NKX3-1) Mouse Monoclonal Antibody [Clone ID: OTI3H7]

Specifications

Product Data
Clone Name	OTI3H7
Applications	IHC
Recommend Dilution	IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human NKX3-1 (NP_006158) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26.2 kDa
Gene Name	NK3 homeobox 1
Database Link	NP_006158 Entrez Gene 4824 Human UniProt ID Q99801
Background	This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]
Synonyms	BAPX2; NKX3; NKX3.1; NKX3A
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Pathways in cancer, Prostate cancer

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