hSET1 (SETD1A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7B7]

Specifications

Product Data
Clone Name	OTI7B7
Applications	IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-320 of human SETD1A(NP_055527) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	185.9 kDa
Gene Name	SET domain containing 1A
Database Link	NP_055527 Entrez Gene 233904 MouseEntrez Gene 9739 Human UniProt ID O15047
Background	SET1A is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. The complex is the analog of the S. cerevisiae Set1/COMPASS complex (Lee and Skalnik, 2005 [PubMed 16253997]). Also see SET1B (MIM 611055). [supplied by OMIM, Mar 2008]
Synonyms	KMT2F; Set1; Set1A
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Lysine degradation

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