DMRT1 Mouse Monoclonal Antibody [Clone ID: OTI4E12]

Specifications

Product Data
Clone Name	OTI4E12
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-210 of human DMRT1(NP_068770) produced in E.coli.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39.3 kDa
Gene Name	doublesex and mab-3 related transcription factor 1
Database Link	NP_068770 Entrez Gene 1761 Human UniProt ID Q9Y5R6
Background	This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]
Synonyms	CT154; DMT1
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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