FTO Mouse Monoclonal Antibody [Clone ID: OTI4A1]

Specifications

Product Data
Clone Name	OTI4A1
Applications	IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human FTO (NP_001073901) produced in HEK293T cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	58.1 kDa
Gene Name	fat mass and obesity associated
Database Link	NP_001073901 Entrez Gene 26383 MouseEntrez Gene 291905 RatEntrez Gene 79068 Human UniProt ID Q9C0B1
Background	This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Synonyms	ALKBH9; BMIQ14; GDFD
Reference Data

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