TRMT12 Mouse Monoclonal Antibody [Clone ID: OTI8C7]

Specifications

Product Data
Clone Name	OTI8C7
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TRMT12 (NP_060426) produced in E.coli.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50.1 kDa
Gene Name	tRNA methyltransferase 12 homolog
Database Link	NP_060426 Entrez Gene 55039 Human UniProt ID Q53H54
Background	Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006). [supplied by OMIM, Mar 2008]. COMPLETENESS: complete on the 3' end.
Synonyms	TRM12; TYW2
Reference Data

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