N myc interactor (NMI) Mouse Monoclonal Antibody [Clone ID: OTI1A8]

Specifications

Product Data
Clone Name	OTI1A8
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-223 of human NMI(NP_004679) produced in E.coli.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34.9 kDa
Gene Name	N-myc and STAT interactor
Database Link	NP_004679 Entrez Gene 9111 Human UniProt ID Q13287
Background	NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]
Synonyms	N-myc (and STAT) interactor; N-myc-interactor; N-myc and STAT interactor; N-myc interactor
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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