CD16 (FCGR3A) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI12H8]

CAT#: TA813635BM

FCGR3A mouse monoclonal antibody, clone OTI12H8, HRP conjugated

Conjugation: Unconjugated Biotin HRP



  View other "OTI12H8" antibodies (4)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Clone Name OTI12H8
Applications FC
Recommend Dilution FLOW 1:100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human FCGR3A (NP_001121065) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation HRP
Storage Condition Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size 29.09 kDa
Gene Name Fc fragment of IgG receptor IIIa
Background This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Synonyms CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20
Reference Data
Protein Families ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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