Human IL-1 beta ELISA Set, 5 x 96-well

Specifications

Product Data
Description	Human IL-1 beta ELISA Set, 5 x 96-well
Size	5 x 96 wells
Format	5 x 96-well
Assay Type	Solid Phase Sandwich ELISA
Assay Length	From sample to end 3h45min
Signal	Colorimetric
Curve Range	15.6-500 pg/ml
Sample Type	Serum, Plasma, Cell culture supernatant
Sample Volume	100 µl
Specificity	Recognizes both natural (pro and mature) and recombinant human IL-1b
Sensitivity	7 pg/ml
Cross Reactivity	No cross reactivity with other human cytokines
Components	ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.
Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Gene Symbol	IL1B
Locus ID	3553

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