Human IL-1 beta ELISpot Set, 20 x 96-well (non-sterile plates)

Specifications

Product Data
Description	Human IL-1 beta ELISpot Set, 20 x 96-well (non-sterile plates)
Size	20 x 96 wells (non-sterile plates)
Format	20 x 96-well (non-sterile plates)
Assay Type	Enzyme-Linked ImmunoSpot (ELISpot)
Assay Length	3h after cell stimulation
Signal	Colorimetric
Specificity	Recognizes natural (pro and mature) human IL-1b
Cross Reactivity	No cross reactivity with other human cytokines
Components	ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, blocking reagent, and 20 non-sterile plates.
Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Gene Symbol	IL1B
Locus ID	3553

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