Human CXCL16 ELISA KIT (96 T)

Specifications

Product Data
Description	Human CXCL16 Immunoassay
Size	96 T
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	4 hours
Signal	Colorimetric
Curve Range	15.62-1000pg/ml
Sample Type	Serum, plasma, Cell culture supernatant
Sample Volume	100 uL
Specificity	This assay recognizes both natural and recombinant human CXCL16.
Sensitivity	8pg/mL
Reactivity	Human
Interference	No significant interference observed with available related molecules.
Components	Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate Standard - lyophilized,1000 pg/ml upon reconstitution,2 vials Concentrated Biotin-Conjugated antibody(100X) - 120 ul/vial,1 vials Concentrated Streptavidin-HRP solution(100X) - 120 ul/vial,1 vial Standard /Sample Diluent - 16 ml/vial,1 bottle Biotin-Conjugate antibody Diluent - 16 ml/vial,1 bottle Streptavidin-HRP Diluent - 16 ml/vial,1 bottle Wash Buffer Concentrate (20x) - 30 ml/vial,1 bottle Substrate Solution - 12 ml/vial,1 bottle Stop Solution - 12 ml/vial,1 bottle Plate Cover Seals,4 pieces
Background	CXCL16 is a member of the chemokine superfamily with putative roles in directing leukocyte migration and functioning as a scavenger receptor. The gene for human CXCL16 predicts a 254 amino acid (aa) protein with an N-terminal signal peptide of 27 aa. It is a putative type I transmembrane protein with a non-ELR motif-containing a CXC chemokine domain, a mucin-like spacer region, a transmembrane domain, and a cytoplasmic domain with consensus tyrosine phosphorylation and SH2 binding sites. CXCL16 and Fractalkine (CX3CL1) constitute the only transmembrane chemokines described, although some CXCL16 activity likely results from a functional 35 kDa soluble form shed from the membrane. Mouse and human CXCL16 share 49% overall aa sequence identity with the greatest degree of similarity found in the chemokine domain. CXCL16 has also been independently cloned as SR-PSOX (scavenger receptor that binds phosphatidylserine and oxidized lipoprotein).
Gene Symbol	CXCL16
Locus ID	58191

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