Human TGF beta 3 (TGFB3) ELISA KIT (96 T)

Specifications

Product Data
Description	Human TGF-β 3 ELISA KIT
Size	96 T
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	4 hours
Signal	Colorimetric
Curve Range	31.25-2000pg/ml
Sample Type	Serum, plasma, Cell culture supernatant
Sample Volume	100 uL
Specificity	This assay recognizes both natural and recombinant human TGF-β3
Sensitivity	16 pg/ml
Reactivity	Human
Interference	No significant interference observed with available related molecules.
Components	Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate Standard - lyophilized,2000 pg/ml upon reconstitution,3 vials Concentrated Biotin-Conjugated antibody,1 vial Concentrated Streptavidin-HRP,1 vial 20 x Assay Buffer,1 bottle Reagent Diluent,1 bottle 20 x PBS,1 bottle 1 M HCl,1 bottle Neutralization Buffer,1 bottle 20 x Wash Buffer Concentrate,1 bottle Substrate Solution ,1 bottle Stop Solution,1 bottle Plate Cover Seals,4 pieces
Background	Vascular endothelial growth factor (TGF-β3) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGFB1, TGFB2, and TGFB3 all function through the same receptor signaling systems. They are members of the large TGF-β superfamily. TGF-β proteins are highly pleiotropic cytokines that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β activation from latency is controlled both spatially and temporally, by multiple pathways that include actions of proteases such as plasmin and MMP9, and/or by thrombospondin 1 or selected integrins. The active form of TGF-β3 is a disulfide-linked homodimer which is generated by activation of the latent TGF-β3 complex. TGF-βs are multifunctional cytokines that activate or repress multiple genes in a wide variety of cell types. Depending on the cell context, TGF-β can control many cellular processes including growth, morphogenesis, and apoptosis.
Gene Symbol	TGFB3

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