CysLT1 (CYSLTR1) (NM_006639) Human 3' UTR Clone

Specifications

Product Data
Product Name	CysLT1 (CYSLTR1) (NM_006639) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CYSLT1; CYSLT1R; CYSLTR; HMTMF81
ACCN	NM_006639
Insert Size	1295 bp
Sequence Data	Insert Sequence (showhide) >SC200960 3’UTR clone of NM_006639 The sequence shown below is from the reference sequence of NM_006639. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAAAAGGAGAAGAAATATGTAAAGTATAGTTTAAACCCATTTCCAGTCCAAACCAATGAAAATAGTTT CCCAAATAAGTATTTTGTCAAATCATTTACAAAAAAAATAAAAATTTTACTTAATATTTTACAAATACT TAACTATTTGGGCCTACAACTCTATCTCATTTATGCATCCACATGATTAGATATTTATAGATATTTTAA GTGCTAAAAATTCGGTCCACAACTATGAACTGAATTATAAATAATTTTGACCACTCACCAGAATTTGGA GAATATTTTTATCTTTGCACTATAAAATATGTCTTATATTAAAGTTTTCCTCTTCAAATAAAAGCTTTA CAAACGATAAAATATATAAAATTAGTCAATAAAAATACATGCAAGCTAAAAGTTATAAAATATAAAACT AGATATAAAATTGGCAAATAGTTCTGAATCATTCTAACATATTCCTTTGCATGCATGCCATCAGATGAG AACTGGAGATGACTCAGGAGCTACATAAAACGTACTGTCACCCTTCTTTGTAGTACTGATTCGCTAGGC AAATTAGGGCCATTTCTTCCAAAAGAGAATGTAAAAGTGCTAGAACAGACTAGTATTCAGCTAAAGGGT CCTAAAAGCACCATACAATGTTCAATATGGCAACAGGAGAAATCTGGTCAAAAGCCAGTTTGTCTCCAG TTTTCTTCTGCCTTTGCCTCAGGCTCCCAAAATTGAATAGTGGAGTTTTAGCTGCTCAGTGAGGTTCCT GTAGAGATTTCTCTCCATCCATGACATATAATTCTTCCTTAAGAAGCCAGACAACTGGCACTCCTATAT ATAAATAGAAGTAATTAAAAACTTATCTGAAGAAGAGAAAAGGAAAAGGAATCTACTTTTCTATATGCC AATTGCTGGGATCAAAATAAACTACAAAGGATTTATGAAGAAAATTGTGAATGTTCACATTACAAATTC TTTTAAGAAGTGCATACATTTATGTATATGTATACAACTATATGTAAGAGATTTTGCTGTATGATATGC ATTATGGGTGAAAGTTCACGATAAGTTTTATTATTGCTTTATTACTTTTTATTGGTATGTTGACAGGAA TATCATGGATATGTTTACAGTGACTTTTATATTACAGTGGACGCTTTGATCTTAAAACAGCCACAACAA CTCATCTACGGCTGAAATATAATATGCGTGGACAAGCTTTTGCTGAAGTGTAGTGTGTCCTTTAAGTTT GTTTTTTAAAAAGTAACTTACCTCAGAAGAAATAAATAACTATAAAGAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006639.4
Synonyms	CYSLT1; CYSLT1R; CYSLTR; HMTMF81
Summary	This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Locus ID	10800
MW	50.9

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