NC2 alpha (DRAP1) (NM_006442) Human 3' UTR Clone

Specifications

Product Data
Product Name	NC2 alpha (DRAP1) (NM_006442) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	NC2-alpha
ACCN	NM_006442
Insert Size	158 bp
Sequence Data	Insert Sequence (showhide) >SC201551 3’UTR clone of NM_006442 The sequence shown below is from the reference sequence of NM_006442. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGAGGACGAAGAAGATTACGACTCCTAGCGCCTTCTGCCCCCCAGACCATAGCCCCTTTTAGTTGGT TTTAGTTGCTCTGGGGGGAGGAGAGAAGGTAGAGCTGTTCTTAAATTTATTAAAAAAAAAAATAAAAGG GAATCTCAGTGTCTGTTCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006442.4
Synonyms	NC2-alpha
Summary	Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008]
Locus ID	10589
MW	6

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