RAIN (RASIP1) (NM_017805) Human 3' UTR Clone

Specifications

Product Data
Product Name	RAIN (RASIP1) (NM_017805) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	RAIN
ACCN	NM_017805
Insert Size	243 bp
Sequence Data	Insert Sequence (showhide) >SC202605 3’UTR clone of NM_017805 The sequence shown below is from the reference sequence of NM_017805. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CATGGGCCTCCCGTGGCCACGTCTCCTTGAGAACCAATACCAAACGAGCGCGCGAACCTTGAAATGTCA CGGGCTTCTACGGACAGGAGCCCGCCTGAGCGCAAAGCTTTCTGGGAGTTGTAGTTCTTATCCCGCGTG GAATGTTGGGAGATTGAGTTTTCGGGAAGTAGCGGATGGGACGGTGGGAGCATGGGCTTAGGATGTGAA TGCCAGGGAGCAATAAAGGTATCCGTGGTATCGGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_017805.3
Synonyms	RAIN
Summary	Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.[UniProtKB/Swiss-Prot Function]
Locus ID	54922
MW	8.8

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