Natriuretic Peptide Receptor B (NPR2) (NM_003995) Human 3' UTR Clone

Specifications

Product Data
Product Name	Natriuretic Peptide Receptor B (NPR2) (NM_003995) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AMDM; ANPb; ANPRB; ECDM; GC-B; GCB; GUC2B; GUCY2B; NPRB; NPRBi; SNSK
ACCN	NM_003995
Insert Size	316 bp
Sequence Data	Insert Sequence (showhide) >SC203972 3’UTR clone of NM_003995 The sequence shown below is from the reference sequence of NM_003995. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGCGGAAAGGACCTCCTGGACTCCTGTAAACCCCCATTCTTTCCAAGTCAGATAGTCTTCTGCTGCTG GTACCTGGGTGGGCAATGGCCACCATGTCTGCACACACCAGAAATGGACATTTTCATATGCAATGGAAA ACAGCCACAAAAAAACCTACCTTATATGGAAGTTGTAGCCCTCTGCAGCTCAGCCCTGTACATATACCT GTCCCTCTCTGGCTTGGTCCCCTTCCTCCCTACTTTCTGTAAATATCTGTATCTAAACCAGAATATTTT GGTCAAATATAAAACAATAATAAAAAAAGTTCTGATGTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003995.4
Synonyms	AMDM; ANPb; ANPRB; ECDM; GC-B; GCB; GUC2B; GUCY2B; NPRB; NPRBi; SNSK
Summary	This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]
Locus ID	4882
MW	11.6

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