Rotatin (RTTN) (NM_173630) Human 3' UTR Clone

Specifications

Product Data
Product Name	Rotatin (RTTN) (NM_173630) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MSSP
ACCN	NM_173630
Insert Size	1150 bp
Sequence Data	Insert Sequence (showhide) >SC204837 3’UTR clone of NM_173630 The sequence shown below is from the reference sequence of NM_173630. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACCTCGTGCAGCTCCTTAATTCTTCCTGAGTGCCATGGGATGCTACACCTTGAAGCTGACAGTCATCA ACAGGGGAGCTAAAGTTGAAGCCAGCTGTGTGTAGCAGCTGTTACCTGAAGACGTGCTACCTCTCTACA AAGTGTTGATCCCCTTCTTTCCCATGAGAGAGAGAACTGGTGATACTCCAACACCGTCCAGTTGTGGCA GCTCTCCAGAAGTAATAGCAGCTGACAACTTTCTGTGCCTTTTCCTTTCTGTTGAAAAGGCATAGAAAG TTCTGGGAACATAAACATTTTTACCCTTTTCTATGCCATTTATTTTGTAAAAATCCTATTTAACAGTTA TTTAATAAAACAATATTTTTAGAAACTAAAAATTGACTAATAATTGCTGCTTACAGACTTTTATCAGTC TCATGAATATTAATTTTAGGAGTTGAAATAAGACACTGTGTCCTGGTTGTTTCTCTCTTTTTTTAAATT TTAACTGATGTAAAATTTGGCTCTGTCAGTGCAAATCCTTATTTTCAAAACTTTCTGTTATCCAGAGCA TCCACACTGGAAAAGGGCTATGTAGAAGTAAGTGTGCATTATTTGTAAAGGGCTGTGTGGAAGTAAATG TACATGATTTGTAAGTAGCTTTCTTAGGCAAGTTTTAGTGATGTTATCTTCTTCCTAGATGACTCTTAA ATCATTACATGTATAATCTTCACCGTTGTCTTCTGCAAGGCTGTGTAATAAAGAAGAAAGAAATAGAGT TGGGGCTGTATAAGCCTGGGTTCAAATTTAGCTCAGCCCAAAACATCATGAAGAATAGAGTAAGACTGA AAAATGCAGAAGATGGCCGGGCTTGGTGGCTCATGCTTATACTTTCAGCTCTTTGGGAGACCGAGGTAG GTGGATCACTTGAGGCCAGGAGTTTGAGACCAGCTTGGGCAACTTGGTGAAATCCCATCTCTCCTAAAA ATACAAAAATTAGCCATTCCTGGTCTTGAGCGTCTATAATCTCAGCTACTCCAGTGGCTGAGGCACGAG AATCTCTTCAACCTGGGAGGCAGGGAGGTTGCAGTGAGCTGAGATCATGCCACTGCATTCCAGCGTGGG TGACAAAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_173630.4
Synonyms	MSSP
Summary	This gene encodes a large protein whose specific function is unknown. Absence of the orthologous protein in mouse results in embryonic lethality with deficient axial rotation, abnormal differentiation of the neural tube, and randomized looping of the heart tube during development. In human, mutations in this gene are associated with polymicrogyria with seizures. In human fibroblasts this protein localizes at the ciliary basal bodies. Given the intracellular localization of this protein and the phenotypic effects of mutations, this gene is suspected of playing a role in the maintenance of normal ciliary structure which in turn effects the developmental process of left-right organ specification, axial rotation, and perhaps notochord development. [provided by RefSeq, Jan 2013]
Locus ID	25914
MW	43.7

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