RPTP mu (PTPRM) (NM_002845) Human 3' UTR Clone

CAT#: SC209279

3' UTR clone of protein tyrosine phosphatase receptor type M (PTPRM) transcript variant 2 for miRNA target validation



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CNY 4845.00


货期*
3周

规格
    • 10 ug

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DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
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Specifications

Product Data
Product Name RPTP mu (PTPRM) (NM_002845) Human 3' UTR Clone
Vector pMirTarget
Synonyms hR-PTPu; PTPRL1; R-PTP-MU; RPTPM; RPTPU
ACCN NM_002845
Insert Size 724 bp
Sequence Data
>SC209279 3’UTR clone of NM_002845
The sequence shown below is from the reference sequence of NM_002845. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
GTGGCCCTGGAATACTTGAATTCTGGCTGATGGTGTAAACAGCTCTGCAAACAATCCCTTTCATACCAC
AAAGCCAAGACGTTCCATGGTATTTGTGCAAAAGAGATGAAGACTTCTCAATATGCTTATTTTGCTTTG
CATAATTGGCTCTTTTTAAGAGCCCAAGAAAGTGTTTCTAAAATTGCTTGCACTGCCCAATCCCAGTAA
TGCTGCTGCCTGACAGAAACACACACACAGCCACAGTTGCCAAATCCCGTACTCCTTGCCACCGGCTTC
CTAGAGCAGCGTAGACAGCTGGTAAACTGAAGAGCACAACTATATTCTTATGAAGGAATTTGTACCTTT
GGGGTATTATTTTGTGGCCCGTGACCCTCGTTATTGTTACAGCTGAGTGTATGTTTTTGTTCTGTGGAG
AATGCTATCTGGCATTATGGTAATATATTATTTTAGGTAATATTTGTACTTTAACATGTTGCATAATAT
ATGCTTATGTAGCTTTCCAGGACTAACAGATAAATGTGTAATGAACAAAGATATGTTGTATGAGTCGTC
GTTTCTGTCAGATTTGTATTGTTTCCAAGGGAAAAGCTTGGGGGAGGACTCAGTTCACAAAATGCAAAA
CTCAACGATCAGATTCACGGACCCAGAGCTTTTCCATGTGTTTATATTGTAAATATTTTTGATTTCATC
AAATTATTTATTCATTAAAAGAAATTTTTGTGAA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_002845.4
Synonyms hR-PTPu; PTPRL1; R-PTP-MU; RPTPM; RPTPU
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Locus ID 5797
MW 27.5
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