HIPK3 (NM_001048200) Human 3' UTR Clone

Specifications

Product Data
Product Name	HIPK3 (NM_001048200) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DYRK6; FIST3; PKY; YAK1
ACCN	NM_001048200
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC210208 3’UTR clone of NM_001048200 The sequence shown below is from the reference sequence of NM_001048200. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACAAAACTCAGCCAGTATCCATATATGTGAAAAACAGTATATTGGGGAAGCTCAATGATACAAACATTT GATTAAAAATAAAAACATGGTATTTAATATTAGCCATGGCACAAGAAAATTATTTTTGAATCATGTAGA CTTGGGTGCAATTTAAACAACTTTGAGCTTTAAAAACTCACTTTTGATGTGTTTTGCACATTTGGTATA ACTTGTCTTTGGTCATGTTATCTTCTTATGTAGTAACTCTAGACAGGTGACTTATGGGAGCAGAAGTCC AGTTTTGCTCCTGCTATTTTTTATAAATTGCCTTCTAACTAGTGCAAGACACGTCTACATTTGGGAAGC CATTCTGTGTACAGACTTAGAGCAACAGATGCACATATGTCAGAATTACAGCATACAAGTGAATTGTAT TATCCGTGTCTTAGTGTATAAATGTTGGGTCACTTACCTAAGAAATTGAGCTATTGTTCTTTACATTTG CATGTGTCTTTTGCATGGGCAAAATGTTGCCTAGACTTTGCTCTTAAATGTTGTTCTAATAATCTCAGC TGCATTGTAAACCGTTCCTACACATAGTGCCTTAAATATTTGAGGTTGTTAATGTTATTACCTATATAT AAATGTTGAGGACTGCAGCACTTAAAATTCAGACCTACTATTTAGTTTCCTTTTGATAGCGTAATGTTC ATTTTTGTTTTTGTGTGGTATGATTTCAGGTAGTAGCTGTTTTTTTCCTTATTAAGAGGGCAGCATGTT TGCTATAGCTGAATTCTGCTGTCTGATTTTTCAGAATGATCTAGCTTCAAGAAAAGCAAGCAGTTAGTA GTGCTTAAGAAAAATTGATTCAGTATCTAATGGATAGTTGATAACTGTCACAGCACAGCATTTTATATA CTGTTAAGTGAAACTGCAATACAATCTAAGTTTATTTTGAGAGTGTTTGCTGTATAATTGGACTTAATA AAATGTTTAGAGGTACAGTAGGCATGACTTTGGGTAGATAATAAAATGCAAAATGCTCATTGATTCATG ATGTGGTTTTATCTTAGCTTGGGCAAACCATGCAGTATTTAATAAATAGTAGCAGAACTTTTACTATTG AAGCTTGAAAAGATGTGAGTTCTTTGTGTGCAATTTTTGATTTATGCATGTGAGAGGGTTTTTTTTTTT TTTAAGTATTTTTACATTGCAGTACTTGTTTTGCTTGTTGGTGATGTTTGCTTATTTAATACATTCCGT CAGGGACAGAAATTACATGCTTTTTTTTCTTTCTAGGAAGTGTGTTGAGTTCCCCCCTTCCCCGACATT TTTTTCTTTTTTGGGTGGTGGTGATGGTAGTGGTTATGTCTGTTTAAATGAAGTTGCTTTTACAGCACC AAAGACTTAATCATCCATTTCCTATATAAAGGTAGCTACTTTTTGCATAGACCTCAAGTATATTGTAGT GTAAAGGTGGAATTTAAGGAAAGGTATTAAATTGAGGCTGTGTTTTAGCTTACAGGCAAGTAATAAATT GTATCATTTATCTTGAATGTATCATAGATAAGCTGCTATATAACGATTGCCACTTCAGATAGCTGTGAA ATTAGGTGATTAACTAGTTGTTATTTAGCCTTCTAATTTCTGTATAAGTCTAATTACATGAATAGAAAT TGGGGTTTTGATTTTTTACTTTGCTTTTCTGTTTGGAGTGTCATTGTAACTACTGTATTGTAAATGGTG GAAAATAATTGCATTTGTTACTTTGGGGTGTGTTATTTGCATCAGTATTTTATCTCTATTAATGTTTGT GCTCATCACTGCATATTAAAAAAACTTGGATGTATCAGTGTAACTTAATTTTTTATTTTCATACTGGCA TTGTAGACACTTGAGAAAGCTGTATCTTGCAGGCTTGACTTAACTTTTTTCCTTAAAAATCTGGAATAT AATCTTACAGCATTTACTGGAATAAACAGTACAAAGCATTGGAGTGTAAAACTCTAGATGTTTTGGAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001048200.3
Synonyms	DYRK6; FIST3; PKY; YAK1
Summary	Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).[UniProtKB/Swiss-Prot Function]
Locus ID	10114
MW	78.5

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