TRIAP1 (NM_016399) Human 3' UTR Clone

Specifications

Product Data
Product Name	TRIAP1 (NM_016399) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HSPC132; MDM35; P53CSV; WF-1
ACCN	NM_016399
Insert Size	938 bp
Sequence Data	Insert Sequence (showhide) >SC211139 3’UTR clone of NM_016399 The sequence shown below is from the reference sequence of NM_016399. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGCAAAGAAAAGCCTGAAAATTCTTCTTGACCTTGACAGTCACCTTGAAGGATTTCGCAAGTCCAGAAA TTGAGGACTCTGGATTTTTGTCAACTAACTCTGTGAACATAGCCATCAGATTTGATGAGGAACTTAGGA GAGAGGAGTTTTATTTCCTCCTTCGATGTTTTCCTCTCAGTTGTAAAAGATGAACTCTTTGAGATGATT TCTCACCTGCTGTGGTATCTTGCAGGAACTGTGTGCTAAAATTGAACAATTTTTTTGAGATTATGGTTG CAATACTTGGCGTGGAATCAGCTTTACATAAATATACCTTGTATGCAAACGATGATAAACTAGTCAGGA TGAGCAGAGCTGCCTGACCTCTTGATTTCTGCTGCAAAAGACATATACACTGTACTGGGGTCACTATTT ATGAAAGCAATTGGTTAGGACCTCTTTTTTTCCTCTCAGGGAACTAATGCTCTGAAAAGGGATCTGGGC ACAACAGTTTCAGTGAGTGCTTTTGAGCACACTTTTATTTTTATATAGTAACTAATGGTTAAGATTGAT GGTGGCCTGGATTAGCAAAGAGGAAGACAGCTTTTAACACAGTTCCCTGCCTTCACAAGAGGTGTCAGA TTAAGATGTGAAAGCTGCAAGAATGTTGCAGTGAACACCATTTCAGAGCTCTCAGTGTGCAGTTCAGGA ATTAAGATACTTGGAATAGCTGTGGAGGAAGAACCTAAATTGCAAAGATCTGCTATTGCCAGCTCTCAA CCCAAGTCAGTGAATTGTCAACCTGCATATCCTAAAAATGTCAAAATGCTGCATCTGGTTAAATGTCGG GGTAGGGGGGAAGCTGAAGGTGCTCGCTTCATTTGCCTTGTTTACTCATCCTGCCCTGTAATGTCTGTA ATCCTGAAGATGGAATAAATTGTAACATTTAGTTTCTATCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_016399.3
Synonyms	HSPC132; MDM35; P53CSV; WF-1
Summary	Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003).[UniProtKB/Swiss-Prot Function]
Locus ID	51499
MW	35

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