Nephrin (NPHS1) (NM_004646) Human 3' UTR Clone

Specifications

Product Data
Product Name	Nephrin (NPHS1) (NM_004646) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CNF; nephrin; NPHN
ACCN	NM_004646
Insert Size	1172 bp
Sequence Data	Insert Sequence (showhide) >SC212742 3’UTR clone of NM_004646 The sequence shown below is from the reference sequence of NM_004646. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCTTCGAGCTGAGGGGACATCTGGTGTAAGAGCCCTCTCAACCCCATTGTCCTGCACCTGCAGGAATT TACACTCCACTGGTCTCTCTCATTACAGCCTGGGCCGAGCTGGTTAGGTGAGCTCCATAAAACCCAAAG GGACTTGGTGTCAGGAGAGGACATGGAGGGGGCTGAGTGACAGAGATGGTTCAGCTGGTACCAGAGTAG AAACAAGGTGCATCCTGGGGTTGGCTTTAGAAACTAAACTTCTCCAAAAGGACAGGGCAGATTGTAAAC GTCGTCTCAAAAATGAAATGCTGCCGGGTGCGGTGACTCACGCCTATAATCCCAGCACTTTGGGAGGCT GAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTAAAACTCCATTTCT ACTAAAAATATAAAAAATTAGCCAGGAGTAGTGGCGCATGCCTGTAGTCCCAGCTACTTGGGAGGCTGA TGCATGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAG CCTGGGCGACAGAGCGAGATTCTGTCTCAAAAAATAAAAATAAAATAAAAATAAAAAATAAAATGCTAT TCTGAGGGTCCCTAAGTGCTTCATGAAGTAAAGTTTTCAGAAGTGGGGAAAGACATATGAAAAACTCTG TTCATTTTGCATTCCATGACGTCTGAAATAGCTAATAATAAGTGGAATTTATGAATCCATGTTGCATCC TACCTATTATTTTATTATTTCCGACAGTTATCTAACACAGGAGGCATAAACTATGACACATGTAAACAT AAGTATGCTCCATAAGCATTAAAATAAACAGACAATCAAAAGAAGCTAGAGGAAAAGAATATGTACTGT GTGTGTGCTTTCGTTTATAGAAATTCTAAAATAGGCAAAACTAATCTACGGTGGCAGAGAGCACAGCAG AGGTTTCCTGGGGCCATGAGAGGAGGGTTGACTGCAAAAAGGCATGGGAGAACTTTCTGAGGTGTTGGA AATATTCTATATAACGATTGTGGTGGTGGTTGCACGGGTGCACAGATTTGTCAAAACTCATTGAACTTT ACACTTAAGATGGGTGCATTTTTATTGTACATAAATGATATCTCAATAAAAGTGATTTTAAAAACAGG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004646.4
Synonyms	CNF; nephrin; NPHN
Summary	This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
Locus ID	4868
MW	43.4

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