splicing factor 1 (SF1) (NM_004630) Human 3' UTR Clone

Specifications

Product Data
Product Name	splicing factor 1 (SF1) (NM_004630) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BBP; D11S636; MBBP; ZCCHC25; ZFM1; ZNF162
ACCN	NM_004630
Insert Size	1242 bp
Sequence Data	Insert Sequence (showhide) >SC213358 3’UTR clone of NM_004630 The sequence shown below is from the reference sequence of NM_004630. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCTCCCCCACCGCCTCCACCACAGAACTAGACTTGTTTTTTAAGAAAATATATATTATATATAGAGAGA ATTGGTCTCGTTTAAACACGCCGAACCTCACCATATGGAGCCAGACATTGGGACGCACGCATGTGATTG TGTGTGCACGCATGTGTGTGTGTGCACGCACTGGGCTGGGCCAAGCGACTGAGGATTCGCTTGGGAACG GGCAGGTGGTAGTAGGGGCGCCAGCTTGGGCTCTCCTGGCGCCCCGTAGCATCGAGTGTCTTCTTTGTC TTCTTTCTCTCCTCACCCAACTCCCTTTGCCTCTCCCCAAACCGGGCCGCCAGGATCCCTCCCCGCGGC GGCGATGGCCCGAGCCATGAGAGTGAGGACTTTCCGCGCCCATTGGTGACCCTTCCAGGCAGACAGCCT CAGCAACGCCCCTGGTGGACAGGATGGTTCGGCAAAGCAGCCTGAGTTATTTTTGTGGACGGAATCGGA ACACGCTGGCTCCATATCGTGAAATTTTTATTAATTTTTTTCTTTTTCCTTTGTTACTTCTTTATCTTT TCCTTTCTTCAGACTCCGTCCAAGGAGATGCTCTCCCCGGTCTTCTGCTGCAATTTAGATTCCTTTCCC TTCTCTCCAGTTCTCCTTCCCTTACCAAGGAGAGGGGAGCAAATGGTTTTGGGCAAGGGCTTTGGCCAT TCATGTCAAGCTGGTTGTGGGTTTTTCAAGGTGCCATAGCCACCCCCAAAGATGTTTGTTTAAAGCGTG GGGTTTTTTAATCTCTGCCACCCTTGTCAAGGGAGTCTTGTAAAGTTGCCGAGGGTAGGTTCATCTCCA GGTTTCGGGATTCCCATCCGTCCTGGCGATCCTGCCAGCAGTGGGTGGGCAGCCTGAGCTCCCTCGGGC TCGCCTGCCAGCCTGGAGTTCTTCCTGTGCTCCTTGATCACCTGAGCTGCCTCAGATTCCATTTGGTCC TCTCCTTCCTGGAAGGCTTCCTTTTATGTTTTGTTTTAATCCCAAATGTCTGAATGTTTTGCAGTGTGT AGGGGTTTGAGCCCCTTGTTCATTCTCCTTCCTTTTTCCTCCCGCTTCCCTCTCCATGAAGTGATTCTG TTGACAATAATGTATACTGCGCGTTCTCTTCACTGGTTTATCTGCAGAAATTTCTCTGGGCTTTTTTCG GTGTTAGATTCAACACTGCGCTAAAGCGGGGATGTTCCATTGAATAAAAGAGCAGTGTGGTTTTCTGGG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004630.4
Synonyms	BBP; D11S636; MBBP; ZCCHC25; ZFM1; ZNF162
Summary	This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Locus ID	7536
MW	46.3

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