RNF43 (NM_017763) Human 3' UTR Clone

Specifications

Product Data
Product Name	RNF43 (NM_017763) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	RNF124; SSPCS; URCC
ACCN	NM_017763
Insert Size	1297 bp
Sequence Data	Insert Sequence (showhide) >SC213683 3’UTR clone of NM_017763 The sequence shown below is from the reference sequence of NM_017763. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCGAGGAGCTGTGTGAACAGGCTGTGTGAGATGTTCAGGCCTAGCTCCAACCAAGAGTGTGCTCCAGA TGTGTTTGGGCCCTACCTGGCACAGAGTCCTGCTCCTGGGAAAGGAAAGGACCACAGCAAACACCATTC TTTTTGCCGTACTTCCTAGAAGCACTGGAAGAGGACTGGTGATGGTGGAGGGTGAGAGGGTGCCGTTTC CTGCTCCAGCTCCAGACCTTGTCTGCAGAAAACATCTGCAGTGCAGCAAATCCATGTCCAGCCAGGCAA CCAGCTGCTGCCTGTGGCGTGTGTGGGCTGGATCCCTTGAAGGCTGAGTTTTTGAGGGCAGAAAGCTAG CTATGGGTAGCCAGGTGTTACAAAGGTGCTGCTCCTTCTCCAACCCCTACTTGGTTTCCCTCACCCCAA GCCTCATGTTCATACCAGCCAGTGGGTTCAGCAGAACGCATGACACCTTATCACCTCCCTCCTTGGGTG AGCTCTGAACACCAGCTTTGGCCCCTCCACAGTAAGGCTGCTACATCAGGGGCAACCCTGGCTCTATCA TTTTCCTTTTTTGCCAAAAGGACCAGTAGCATAGGTGAGCCCTGAGCACTAAAAGGAGGGGTCCCTGAA GCTTTCCCACTATAGTGTGGAGTTCTGTCCCTGAGGTGGGTACAGCAGCCTTGGTTCCTCTGGGGGTTG AGAATAAGAATAGTGGGGAGGGAAAAACTCCTCCTTGAAGATTTCCTGTCTCAGAGTCCCAGAGAGGTA GAAAGGAGGAATTTCTGCTGGACTTTATCTGGGCAGAGGAAGGATGGAATGAAGGTAGAAAAGGCAGAA TTACAGCTGAGCGGGGACAACAAAGAGTTCTTCTCTGGGAAAAGTTTTGTCTTAGAGCAAGGATGGAAA ATGGGGACAACAAAGGAAAAGCAAAGTGTGACCCTTGGGTTTGGACAGCCCAGAGGCCCAGCTCCCCAG TATAAGCCATACAGGCCAGGGACCCACAGGAGAGTGGATTAGAGCACAAGTCTGGCCTCACTGAGTGGA CAAGAGCTGATGGGCCTCATCAGGGTGACATTCACCCCAGGGCAGCCTGACCACTCTTGGCCCCTCAGG CATTATCCCATTTGGAATGTGAATGTGGTGGCAAAGTGGGCAGAGGACCCCACCTGGGAACCTTTTTCC CTCAGTTAGTGGGGAGACTAGCACCTAGGTACCCACATGGGTATTTATATCTGAACCAGACAGACGCTT GAATCAGGCACTATGTTAAGAAATATATTTATTTGCTAATATATTTATCCACAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_017763.6
Synonyms	RNF124; SSPCS; URCC
Summary	The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Locus ID	54894
MW	48.9

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