Mel18 (PCGF2) (NM_007144) Human 3' UTR Clone

Specifications

Product Data
Product Name	Mel18 (PCGF2) (NM_007144) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MEL-18; RNF110; TPFS; ZNF144
ACCN	NM_007144
Insert Size	1355 bp
Sequence Data	Insert Sequence (showhide) >SC214053 3’UTR clone of NM_007144 The sequence shown below is from the reference sequence of NM_007144. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACGGCGCTCCCGTGCCCCCCTTAACTTGAGGCCAGGGACCCTCTCCCTTCTTCCAGCCAAGCCTCTCC ACTCCTTCCACTTTTTCTGGGCCCTTTTTTCCACCTCTTCTACTTTCCCCAGCTCTTCCCACCTTGGGG GTGGGGGGCGGGTTTTATAAATAAATATATATATATATGTACATAGGAAAAACCAAATATACATACTTA TTTTCTATGGACCAACCAGATTAATTTAAATGCCACAGGAAACAAACTTTATGTGTGTGTGTATGTGTG GAAAATGGTGTTCATTTTTTTTGGGGGGGGTCTTGTGTAATTTGCTGTTTTTGGGGGTGCCTGGAGATG AACTGGATGGGCCACTGGAGTCTCAATAAAGCTCTGCACCATCCTCGCTGTTTCCCAAGGCAGGTGGTG TGTTGGGGGCCCCTTCAGACCCAAAGCTTTAGGCATGATTCCAACTGGCTGCATATAGGAGTCAGTTAG AATCGTTTCTTTCTCTCCCCGTTTCTCTCCCCATCTTGGCTGCTGTCCTGCCTCTGACCAGTGGCCGCC CCCCACGTTGTTGAATGTCCAGAAATTGCTAAGAACAGTGCCTTTTACAAATGCAGTTTATCCCTGGTT CTGAGGAGCAAGTGCAGGGTGGAGGTGGCACCTGCATCACCTCCTCCTCTTGCAGTGGAAACTTTGTGC AAAGAATAGATAGTTCTGCCTCTTTTTTTTTTTTTCCTGTGTGTGTGGCCTTTGCATCATTTATCTTGT GGAAAAGAAGATTCAGGCCCTGAGAGGTCTCAGCTCTTGGAGGAGGGCTAAGGCTTTAGCATTGTGAAG CGCTGCACCCCCACCAACCTTACCCTCACCGGGGAACCCTCACTAGCAGGACTGGTGGTGGAGTCTCAC CTGGGGCCTAGAGTGGAAGTGGGGGTGGGTTAACCTCACACAAGCACAGATCCCAGACTTTGCCAGAGG CAAACAGCCTTCCAATTGCCCCTCCACCCCCAGCTGAGGCCCGGTCACCTGGTCAGGACAGAGCAACTG CATCTAAAAGCACAAGAAGACAGAAACCTGTAAGCTCTGACCCCACCCCCACCCCTTGAGAGGTCAGCG GACCACCTCCTTAGGGACAGACCCTGGCAGGTCGCTGCCCACCGAGATTTCCTCAAGTGTGCATAGATC TGAGAGGAGTCGGGAGTCGAGACTCGAGATTCCATCATAGCGTAGGTGTGTGGGGTTGGGAGCCCCCTG ATGGGCTTGTCTGTGTTTGCACCTTGTCCTGTGTCTGAGGTCCTGTGACTGTACCCTCCTTTGCCCTGG GACATCTGTATCTCTTGGCTTTGTAATAAATGCTGCATACTTTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_007144.3
Synonyms	MEL-18; RNF110; TPFS; ZNF144
Summary	The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008]
Locus ID	7703
MW	50.2

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