C3IP1 (KLHL12) (NM_021633) Human 3' UTR Clone

Specifications

Product Data
Product Name	C3IP1 (KLHL12) (NM_021633) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C3IP1; DKIR
ACCN	NM_021633
Insert Size	1443 bp
Sequence Data	Insert Sequence (showhide) >SC214555 3’UTR clone of NM_021633 The sequence shown below is from the reference sequence of NM_021633. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCTGGTGTTTGTGTTCTCCGCGAGAAGTGACCATTGTTGGAGCACCATCCAGAGCTAGTGACCAGTCCA GTGGACAGTTAGTGGGAGAATCAAAAATCCTTTCCAGAATGTCTGTTTCTCACTATGTGCACCGGGTGA TTACAGGCACCAGTGCAGTGATGATTGTACTTATTTGACACATACTCCCCGTCGTCCTGGTTCTTGTTC CTGAGAAGGGTGGGTAACAGATATTCCAGGAAAAAGAATGCACATTGAATGGATGTGAGAGACCACATT GCCTCTCCCACTGCTTTGGGGAGCACTTTCCTGTCATTTCTAACTTACCACATGCTTGGTGTACTATAT GTATGTTGTGCCTCATATGTTGCAAAGAACTAAGGTGAGTATAGCCTACTAGATATGGGCAATATCCAG CCTAGATGATTGGAAAGATACCAGTTTAAGTAAACTTGGTAAAATCCAAGTCTTTTTTTTTTTTTCCAG GAACAACTACATTTTCTCATATACAGGTAGCTAGGGGCAACACAGTTCCATTCTAGAGGGAAACAAAAG GGAGAGCCCCACAAAACTTTGGGGACAAGGGAGAGAGAGACTCATCTGACACTTCTTTTGGAGGTCAGG ATTTGTATATCAGAATTGAAGTTAGAATTAAGTGAATTAAACTGAATTTGATTGTGAGTGAACCTAGAA CAGCACTGAAGTATTACATAACCTGGAAGACTGAGAAGGGTATATTATTTGAAGGATCTTTTTATTTCC CCGAGGTCTTTCGCACTGGAGACAGCATAAAAGAGTGAACAAATGTTGGGATGAGAGAAGATGACATCA ATGTGGGAGTTCAGTATAACTGGGGATAAACTAGAAGAACCTGTGATTTTACAGTCATCTTATTACCTG CCAGGGCTCATCTAGCCATGGCAATGTTTGCCTTGAATGGGGGTGAAAGCCTTTCTTTGTTGGATCAAA TACTACTACACTATTACACTTCCACACTATTTATTTGGGGATGGGCTGGGAGTGACAGTAGCCTAGTAG TTCAGCTACCTGATTACTGCCCCATTCTTTTAGAAGCACATGTCTGCCAAGGAGTGGTTTGTACTGCTG TGTTTGGTACATCTAGTCTTTTTTCTGCTATAAGTTTTCCTTACCTGTCCTTTAGTGTAGATTTTATTC ATCACAGGACAGAATAATCAAGGACAACCAAAATCCTTTTGTTAGTTTCAGTACCTCAGCTATCAACAT TTCTGAGCTACCATTCAATGTTCCTCTGTGTCATGGAGTGAAATTCTTGTTTTGTGGGTATTAGGAGTG TGGGAATGTGATAACCTAAACAACCTTTGCTCTGAAATTCCATTTTTCCCTCTTTCCCTGAGTTGTATT GACCTACAGAGTTAATTTCCTTTGTATTTTTTTAAGAAAATATTAAAAATCAACGGTCTCAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_021633.4
Synonyms	C3IP1; DKIR
Summary	This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Locus ID	59349
MW	55.9

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