RBM38 (NM_017495) Human 3' UTR Clone

Specifications

Product Data
Product Name	RBM38 (NM_017495) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	dJ800J21.2; HSRNASEB; RNPC1; SEB4B; SEB4D
ACCN	NM_017495
Insert Size	1517 bp
Sequence Data	Insert Sequence (showhide) >SC214978 3’UTR clone of NM_017495 The sequence shown below is from the reference sequence of NM_017495. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCGCAGCTGCAGCCTGACAGGATGCAGTGAGGGGCGTTCCTGCCCCGAGGACTGTGGCATTGTCACCTT CACAGCAGACAGAGCTGCCAGGCCATGATGGGCTGGCGACAGCCCGGCTGAGCTTCAGTGAGGTGCCAC CAGCACCCGTGCCTCCGAAGACCGCTCGGGCATTCCGCCTGCGCCCTGGGACAGCGGAGAGACGGCTTC TCTTTAATCTAGGTCCCATTGTGTCTTGAGGGAGGACTTTAAGAATGACTGAGAACTATTTAAAGACGC AATCCCAGGTTCCTTGCACACCATGGCAGCCTCTCCTTGCACCTTCTCCTGCCTCTCCACACTCCAGGT TCCCTCAGGCTTGTGTCCCCACTGCTGCATCGTGGCGGGGTGTCACAGACCCTCTGCAGCCCCTGGCTG CCCTGGACTGTGCAGAGATGCCTGACTCCAGGGAAACCTGAAAGCAAGAAGTTAATGGACTGTTTATTG TAACTTGATCCTCCCGAGCTGTGAGCGCAGTCTGAGGTGTGAGGACACGGCCTCCTGTTGGAGTCCCAT TTTCTCCATCAGGGCACGTGGGCGGCTTCCTCAAGCCCGGAGGAGCTCCCAGGCGCACAGGGGCCGCCG GTAACAGGGGCCGCCGGCCAAAGGCCCCTTTCCAGTCATAGCACTGAAGTTGCAACTTTTTTCTTGTAA TTGTTTTGCTACTAAGATAATTTCAGAAGTTCAGTCTATTTTTTCAGCGGATACTGCCGCCACCAAGAA TCCAAAACCTATTTTTGACTTGGAGAGACTTGCTTTTGTTGGTTCCGCCCGTGGAGACGACGATAGTGT TTCTGTATAATAAAGTGTCTGCCGGCTCGCGGGCCAGGATCCTCTCGGTGGGATGGGCACCACAGACAG GAGGCCCCTCAGGCCCGTGCGGGCCACTGTCTGCTGCCGCCTGCCGGGGTGGCAGAGTGAGTTGTCTCA GGACCCCGTCACTGCGACGTTGACACTCCTCTCCCTTCCCTTCCTCCCCAACTCCCCAAACACTGTGGA AGGGGAGAAGGAAGTGATCCACAGCATTCAGGCCACTTGGGGTCTAGACCATGGTGGTGCCAGCCTGGG GGGGGCAGTGGCCCTCAGCTCTGCCCGCTGGAGCGGTTGAGTGCAGAAGGGTGCGCCTCTTCCCTCTAC CCCCGCACCACCTGCTGTGTGCCAGCCTGAGACGGTTCCTGCCTGTCTTGGGGGTTGGTGGAGGGTGGA GGCAGTTCTGCCAGCCGTGGCAGGGCTGCTATGGGGCATCCAGGGCTGTGGGGGTCTGGAGGAGGGGAC ATGAGGTGAGAGGTATCCTGGCCGAGGGCGGGGGGCAGCGGGGGGTCTCCCTCCGGACCTACCTCAGGG AGCTGAGCGTGCAGGCGCTCCAGGGCAGGCCTGGGACAGAGTCAAGGCTCAGAGAATAAAGGTAGCTAA TCTCATCATAATATTTTTATTAGAATGTTCTGATGATAAAAATAAAACTTGTTTTCTTTAAAGAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_017495.6
Synonyms	dJ800J21.2; HSRNASEB; RNPC1; SEB4B; SEB4D
Summary	RNA-binding protein that specifically bind the 3' UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.[UniProtKB/Swiss-Prot Function]
Locus ID	55544
MW	55

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