TTC3 (NM_003316) Human 3' UTR Clone

Specifications

Product Data
Product Name	TTC3 (NM_003316) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DCRR1; RNF105; TPRDIII
ACCN	NM_003316
Insert Size	1574 bp
Sequence Data	Insert Sequence (showhide) >SC215227 3’UTR clone of NM_003316 The sequence shown below is from the reference sequence of NM_003316. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGAGCTGCCTTCCTGCTCTTCTAGGTAGTCACACTTCACTAAAGTGTCATCCACCAGTGTGTTGAAT CCGAAGAATGACAATTTTCTACCACTGGTGTAAAAAACAAACATTTGAAGACCCTTGTGCATTGTGTGT CACAAAGCTAAATACATGGAAATCGTTAATATCGCTGATATTAAGTAATTTCCCCACTCTGAGTGAATA CTTTGATGATTGCCAACAGTGGCTAATAAAATGACGGCTACCACACTCATGGGTCACTGGGGCTGCGCA GGGCTCTTTGAGGTGGGTGGCTTCTTTTGGAAAGTACTATGAACGTCTCGAAGCAGTATTCTAGTGATA AGAATTCTTAACATAGCCAAGCGCCCCACGTTTGTTCCCCACGTTTGTTCCCCTTTTCTGTTTGAAAAA CCTGTTCTGGTAGCTCCACAAGAGAGATGATACTGACTTTTTAAATTTTTTACAAGAGTCTGTATTCCT GATATGCCTATATTTTTCCTCAAAGATTCTGCATTTTAAGGATGGGCATAAGCAAACTATATTTTAATA ATTTATAGTTAATGTTAAAATATTGGCTGATTTAGACCAAAAGATTCAAATCTCCTCTTTGTGAAATCC CATCTGCATTTGATTTTTTATTATTTTATGTTCCCCCGTTAGATTGTTTTAAGTGTTTGCTTTTCATCT TTTATAGATGTAATCTGATTTTCAAAAATCATTAACACTTTTTAATTAGTATCGACTAAGACTTTTTCC CCCTGGAATCGAGGCTGTGTGTCCGTCATCCCAGCCCCCGGTTGGAGCCTGCTCTTTGAACTCCGCTGC CTTCCTTAGCAGCTTCTGTCCTCTTCTGTGAGTCAGTCAGCGAGTGCTTGGGATCCGCATCCAGCCGTG CTGAGCACACAACAGGCTGTGTGTGGAAATGGCCACCACCATTCTCCTTCCCCACCCCACCACAAAAAG AGAAGCTGTGTCTTTAGACAACCCTGAGGTATCTGTGTTACAATCGTTCTGTGTTTGATATTTGTGTAA AGTATGCATGCAGTCTTGTACTGTGACCTAAGAACAAAACTGTAACTGCATTAGAAACCATGAAAAAAT TAGATATTGTTTTGTGACTTTTAGACAGTGGTAAATATAGAACCATGAATTCTGGTCACATTCCATTTC TCTCCAACATGAAGGATCAAAAAATGTTTTTCAATGTGTTCTTTGTTCCACTGGAAACTTAGAGTCATG AGTTTATGAGCTGATTTGGTCACCTTCCTCTGCCTTTGTTCACTGTGAGTTCTGATGTCTTAGTGACTT AGTTCTTAGAAGCTCACGCCTTAGTTTGAAACAGATTCTCCACGGTGGTCCCCAAAACACTGTCTGCAT ATCCATAAGAATTGAGCGCTATGGGTGTTAACGTGCATGAGGATCAGTTTGCAGCAGCAAGTACAAAAG GAGAAGAGGAACATCCGTTGAATGAGTGTGTTTTGTACATAACTTCAGATACTTGTGAACATGCCTTAT ATTTGTCCAACAACTGTCAGAATAAAGAACATTCTAAAATGAGAAGTTCACTGTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003316.4
Synonyms	DCRR1; RNF105; TPRDIII
Summary	E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.[UniProtKB/Swiss-Prot Function]
Locus ID	7267
MW	60

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