ALKBH5 (NM_017758) Human 3' UTR Clone

Specifications

Product Data
Product Name	ALKBH5 (NM_017758) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ABH5; OFOXD; OFOXD1
ACCN	NM_017758
Insert Size	1588 bp
Sequence Data	Insert Sequence (showhide) >SC215390 3’UTR clone of NM_017758 The sequence shown below is from the reference sequence of NM_017758. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCCCGAAAGGTGAAGATGCGGCGGCACTGAGTCTACCCGCCGCCCTCCTGGGAACTCTGGCTCATCCTT ACGTAGTTGCCCCTCCTTTTGTTTTGAGGGTTTTGTTTTTGTTCATTGGGGGGTTTTTGTTTTTTGTTT TTTGTTTTTTTTGATTCTATATATTTTTCCTTGGTTTTGTTGCCTGTTAGGGCTGAAGAATAGAATTGG CCAGGACCTAGGTTCTCATATTCTTGGTATTCCTCCTGGATGGAAAGGCTGTTGGCATCAATAGGGGAC AGAGGCTGATGCTGGAGTGGCCAGTAGAGGTGGTGGAGCAGAGCAGCCATCTTTTAAGTGGGGCTGTAT CAGGCTGGGTTTATTTAAAAGCAACAAAATGTTTTGGTTAAGAAAATTATTTTGCTTTCAGTGTAAATC TTCGCAGTGTTCTAAACAAAGTTCAGTCTTCTGCTCGCCCCTTTCCCTCACTGATGTCTGCACTTGGTT GAGGTCTCCTGGAGCCTCACAGGCTCTGCTGTTCTCCACTTCTCACCTGCCATCCACGCCCTGCAAGCT CATGCAAACACCCTTTCTTCCTCCTGCGGCAGAGTTGTTCAGGTTGCCTGGGCAGGGGCTTAAACAGTG CCAGCCCCTGCCATCCCAAAGCTATTGTTAAGCCCCCCAGGCGTCCTCCACCCACGCCCACTAGCCTGC CATGTCCACAGTTCCTTGGGCTGCTGAGGGGCTAGTGCAGTGGTCCTGACCTCTCTTATCAAGAGCACA CTTCTTTGCTGGTTGCTCCTTTTGAGCATATGCGTGTGATTATTTGGAACAGTTAGACTTGCCACGTTG GGTCAGTTTTAGAAATTGTTTCTAGCTAGAGGGACTGGTGTCCTTCCAAGTCTAGCATTTGGGGTATGG AAAATTGTTGTGGTGTGTGGTAGGGTTTTTGTTTTCTTTTTTGAGTTTTTTTTCCCCCTTTAGTCTCCT GGCTTTTTCCTTTCCCTTCCCTTCTCCACTGGCCAGCTTGGGCCTCATCCTCATGTCATCCTTCTAGGA AGGCGCCTGCCCCATCTTGTCTGCCGGCAGCATGCATCCAAGGCCAGAGCTCAGGCCTGCAGACTGGGC TGGTGCCTCCTCCGCTTCAGGGTATGGGAGTTGGTGAAGGGGCTTTCAAAAAATAATAAGGAAAAAAAG GTAAAGTCTTTGGTAGCTTCTATCCACTCAGATCCTGGAAGGCAGCAAGGTTTTGTGGATCTAGATTCA TTAGGAATGTCTTCTTGTCAGCCAGGCCAGGACCCGGGCTTGCCAAGAGCAGAGGCCCTCCCAGCAACC AGGATACCACCACTTTGGGGGCTTTGTGTACAGAGGTCCGGGTCTGAGACCTCATAGGCTGCAGAAATC TGGGGCAGCCACCATCAAGAAGCCCCTCTCAGGGGCCAGAACTCCTTTGCCAGCGTGGATTTCTCAAGT CGGGACTGCATAATTAAAGCAGTTGCAGTTTTATTTTTTTTACAGCTTTTTTCCCAAAAATGATTTGTA GTTGTGTGTGCAGCACTTCGCCCTGATATGTGTGCTCTACAATAAAAACCAAATCTAATATATTTTGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_017758.4
Synonyms	ABH5; OFOXD; OFOXD1
Summary	Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24489119, PubMed:24616105, PubMed:24778178). Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24489119, PubMed:24616105, PubMed:24778178). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3' UTR mRNAs in male germ cells (By similarity).[UniProtKB/Swiss-Prot Function]
Locus ID	54890
MW	58.8

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