TDP1 (NM_018319) Human 3' UTR Clone

Specifications

Product Data
Product Name	TDP1 (NM_018319) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_018319
Insert Size	1651 bp
Sequence Data	Insert Sequence (showhide) >SC215754 3’UTR clone of NM_018319 The sequence shown below is from the reference sequence of NM_018319. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACGCATGGGAACATGTGGGTGCCCTCCTGAGAATCTTGAGGCACTGTGAAATTTAAGTGTAAGACATTG AGCCACAAACATGGAATCTCTTCTTTGTACTGGATGTCCACTTCCCTTAAAGTCTTATTTGCACCCTTA CAAAATCTTTCCAAAGGTCACTCTTATGAATGGATGTTGGTTATACTTTTAATGGACATTAACATTCCT AATAAAGTATTAGTTTCTTAATTCACTTTTATATGTTTTGGAAAGAAAATTAGTGAACTTCTCTATGTT AAAAATACGTACTGCTTGAGTATCCCCTGTCTGAAATGCTTGGGACCAGAAGTGTTTCAGCTTTTGGAT TTTTTTGAATTTTGGAATATTTGCATAGCATAATGAGATATCTTGGGAATGGGACCCAAATCTAAACAC AAAATTCATTTATGTTTCATATACACCTTATATACAATAACCTAAAGGTGATTTTATATGATATTTTGA GTAATTTTATGCATGAAACAAAGTTTTGACAGGCTTTTGACCGTGATTCATCACATGAGTTCAGGCATG GAAATTTTCATTTGGAGCATCATGTCAGCACTCAAAAAGTTCTGGATCTTGGAGCAGTTCAGATTTTCA GATTAGGGATGCTCAAATCTATATAGATATAAAATTATCCTCACAGTAACATAGAATCTCTTGGTGCTG TCAGCTGTTGGGAATTGAAGATTGACTTTGTGCTTCCACCCTCCATCCAGAAAGGCACCCTTCATTCCA CCAGAACTTTACCCAGGAAGAACACGATCATTTCCTTTTTCACCGATGCCCTCTCTCAGCTTTCTGAGT ACGTCTCTTGGGGTCGCTGGAGGTGATCCTAGGATCTGTCTCTGAGACCAATGTGCTGTTTCAGCCCCC TGCAGCTAAGAATTGTATTGACTGTCCTCACAGCGGCTTTTCATAGCTTTCAGCTTCAGCTTTACGAGG CTTCTCCTCTCTCCCTGGCACCCTGCTGGCTGCCTCACTGCTTACAGACAGGTCCCACCAAACCCAAAC ACCTGCCTAGGGTAAATGGGTCTCTCTTCTATCCCCAGAAACTTTCAGAGGAAGCAGCTCATAGAAACA TACAAAAGCACACAAGTATTTTGGGAAAAAATCCTAAAAGGTGACTTAATTTGATGCCTTAAATTCACA AGTGAGGAAGCTAAGGCCTAGAAGGTTAAGGATGTCCCCAGGGTCACACAGTGAGCGGGGCTCAGAGCT TGAGTGTCTTTGTGCTTTGTGTACATTGTGTTCTCCCTAGGGTGCTTTAGACCCTGTTTGTTTTCTTCT GCATGAGGCTGATTTCCAGTTTGTCATCAACCTCTTTATCTTATAATTTAGGATAGAGTTGAACGTTAG TCTTGAAAGATTTTCTAAAGTAGTCTTTCAAACTGTTCCTCAGAGGCCTAGGATTTTCCAAAAGTACCT TAGGAACCTTGTAGGCTGCAGTGGGGGTGTGGCGATAGAGCAGGAGGCAGGGAGACAGGGCTGCAGGGC CTCCCACCTTCCAACAGACAGGCTCTGCTGTATCTGTTGTACATACTGGGATTCTGTAAAGGACATTAT CTGGGGTGTTGTATGTATTTTTGTGTGTTCTGCTTTTTTTAAATAAACTTGAAAAGCTACTGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_018319.4
Summary	The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
Locus ID	55775
MW	62.5

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