UFL1 (NM_015323) Human 3' UTR Clone

Specifications

Product Data
Product Name	UFL1 (NM_015323) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	KIAA0776; Maxer; NLBP; RCAD
ACCN	NM_015323
Insert Size	1803 bp
Sequence Data	Insert Sequence (showhide) >SC216441 3’UTR clone of NM_015323 The sequence shown below is from the reference sequence of NM_015323. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCTAGGAAATCATCTGTGACGGAAGAGTAATGATCTTAATTTACATTTGTCATATAGTAAGCATTTTCC CCCAAGGTTGAAGGTGAGTGGTCACAAAAAAGTAGTCACTATACAACTCCCCTCTCCCTGCAAAAACCA CCTCATACACACACAATTCAGTTAAAACAGTAGTATTGTATTAAATGTAAATCTTAAAAAGATGTGAAT TTTTGTAAATTGGGTTCTTCATGGAAGTTTTTTTCCACCTGATTTTCACACAAATACTATATGAAATTT TTCACATTATTTTCACATAATTTTAAAAATTACATATTTCAGGTTTGTTCTCTTTCCAAATGTTGAATG AAAAACAAATTTTCCAATCCATTTATCCCTGGGGAAGGATTCATTTGTTGCGAGTGCCAGTATACTTAA ATGTATACTTTATATACATTTAAGCAGAAATTTAAAATGTGGTCTTTTTTTTTTAAAAGAAACACTTCT GTGTCAGAAATGAAAATAAATCATGTTTTTTATTTTTAAATAGAAAGCACTTCAAAACTAAAATACAGA AATTTACAAAAAAGAAAAATTATTACTAAGCCCTTGCTCTTATTTTTGGCAGAATAAACATTGATTTTG GTTGGGGCTGCAAGGATGCCTTTACAGGTGCACAAGAACGCTAGAGTGGCCCATGCATTGCTGTGTTCT CTTCTAAAACAAGCTACTAACAAGAGAGAGAACACATGCAATTTATTACCAGTAAGCATAAGTCATATT TAACATTGGAATAACTAAGCATTTTATACAAAGATTTTTCTTTGACCCAGTTTGCATTTGTACATTTTA TTTTTTTAGTTCAACAGCTGCTCTGTCACATAATACTTTGTAAATACTAGTGTGAAAAACAGATAGGAT GCCTTTTCCAGTGGTAGGAGCATCTGTAAGTGCATTTAAATCATTAGAAGCTTTTTTCCAAAACTAGAA ACCCTTATTAAAAAATAGACATTTTTTTCTAAAGATTATTAGTTAAAAATAACTAAAAGAGTTCCTTAG AGTAATCATTTCAACCAAATGAATTTCAAGCAACAACTTACTTACTATTTATCAAAAAGGGATTTAATT ATTTTGAATATAATTATAAATTAAATTTCAAATATTTAAAAATACTATTTTATATAATTCCTTATGACA TTTTAAACTTTATATTTTAAAATATTTGAATACGAAAAGATCAGTCTACCTCTACTCCATTCTAGACAA AGTATTAATCCTTAGTGAAAGTAATTAATTAAATTGCCAACTTGGCATTATTATTAAACTTGATAGGAA CGCAACATTAAATTTAAAAATGTTTTCCCGTGGGTAATTTTCTATTATATATTTTCATATGGGCAAAGG GAAAAAATGATAAATCCTCTGTAATCACAAACCCCAATTTCGTTTTGTTTATTCAGCTTCTAAAATATT GAACACCCAGACTTTTAATTCAACCTTTAAGAACCTTATCATTTATGTTTCAGTAGATATCAAAGTAAT CCATGTTTGTGTCAAATGATCATAGAAAATAAATAGAAGAGACAGTGAAGCAAGTAAAAAGAAAAGCAT TGTTTTAATTTGTTTGCATTAATTTTTTTCATTTGTCAAAATGCTTCTTTTGTTGCCACAGTAAAGAAC AGTTTTTATTGTTTTGTAAGTAAAATTACGTAGCTGATTTTGTATGTAAAGATTAATTTCCATAATAAA AATTATTGTATGTTTACTGTGATCTTAATGGGCAGGGTTAAGAAAGTTATTTAAAATAAAGTTACCTAT TCTACTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015323.5
Synonyms	KIAA0776; Maxer; NLBP; RCAD
Summary	E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysine residues of proteins that may play a crucial role in a number of cellular processes. Mediates DDRGK1 ufmylation and may regulate the proteasomal degradation of DDRGK1 and CDK5RAP3 thereby modulating NF-kappa-B signaling (PubMed:20018847, PubMed:20164180, PubMed:20228063, PubMed:25219498). May also play a role in nuclear receptor-mediated transcription through TRIP4 ufmylation (PubMed:25219498). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress (PubMed:23152784). Anchors CDK5RAP3 in the cytoplasm, preventing its translocation to the nucleus which allows expression of the CCND1 cyclin and progression of cells through the G1/S transition (PubMed:20531390).[UniProtKB/Swiss-Prot Function]
Locus ID	23376
MW	71.6

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