Bpifa1 (NM_011126) Mouse Untagged Clone
CAT＃: MC203603
Bpifa1 (untagged) - Mouse palate, lung, and nasal epithelium associated (Plunc), (10ug)
CNY 2400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | LUNX; NASG; Plunc; SPLUNC1; SPURT |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC054375
GGACGACCACTGAGACCTTGAGACTCAGACACCAAGAGAGATGTTTCTAGTTGGGAGCCTCGTTGTCCTC TGTGGGCTGCTGGCCCACAGCACAGCACAGCTGGCAGGCTTGCCATTGCCCCTGGGCCAGGGTCCACCCT TGCCACTGAACCAGGGCCCACCGTTGCCACTGAACCAGGGCCAGCTGTTGCCCCTGGCTCAGGGTCTGCC TTTGGCTGTAAGCCCAGCACTGCCTTCAAATCCCACAGATCTTCTTGCTGGAAAATTCACAGATGCTCTC AGCGGTGGCCTGCTGTCTGGGGGGCTGCTGGGCATTTTGGAAAATATTCCACTCCTGGATGTTATAAAGT CTGGAGGAGGCAATTCTAATGGCCTTGTTGGGGGCCTGCTGGGAAAACTGACGTCATCAGTTCCTCTCCT GAACAACATCCTCGACATAAAAATCACTGATCCGCAGCTGCTAGAACTTGGTCTTGTGCAGAGTCCTGAT GGCCATCGTCTCTATGTCACCATCCCTCTGGGCTTGACACTCAACGTAAATATGCCCGTAGTTGGAAGTC TTTTGCAATTGGCTGTGAAGCTGAACATTACTGCAGAAGTCTTAGCCGTGAAAGACAATCAGGGGAGGAT TCATCTGGTTCTTGGTGACTGCACCCACTCCCCTGGCAGCCTGAAAATCAGCTTGCTCAATGGAGTCACT CCTGTTCAAAGCTTTTTAGACAACCTCACAGGGATATTGACTAAAGTCCTTCCTGAGCTGATCCAGGGCA AGGTATGTCCTCTGGTCAATGGGATTCTCAGCGGTTTGGATGTCACCCTGGTGCACAACATTGCTGAATT ACTGATCCATGGACTACAGTTTGTCATCAAAGTTTAGGCATCCCAGGAAGGAAGGCTATCTTGGCTGAGC TGAATCATTTCTTGCTGCTCAGTCTCCTGCCTCTTGCCCAGTCTCCCATGGCTCACAGAAAGGGGCCCAC ATCCTGGAAAATTATGTCTTCCTTCTCCTCACGGAGCCTGATCTCTTCCCATCAGGCACGATTAATCCTG TGATCCTCACTAAATAAAATAGCTCTTCATCTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAATTAAAAAAAAAAAAAAAAAAAAAAAAAAAG |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_011126 |
| Insert Size | 837 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC054375, AAH54375 |
| RefSeq Size | 1156 bp |
| RefSeq ORF | 837 bp |
| Locus ID | 18843 |
| UniProt ID | P97361 |
| Gene Summary | Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC) (By similarity). Plays a role in the innate immune responses of the upper airways (PubMed:23499554). Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae (PubMed:23499554). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus (By similarity). Plays a role in the airway inflammatory response after exposure to irritants (By similarity). May attract macrophages and neutrophils (By similarity).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG203753 | Bpifa1 (tGFP-tagged) - Mouse palate, lung, and nasal epithelium carcinoma associated (Plunc) |
CNY 2850.00 |
|
| MR203753 | Bpifa1 (Myc-DDK-tagged) - Mouse palate, lung, and nasal epithelium associated (Plunc) |
CNY 2400.00 |
|
| MR203753L3 | Lenti ORF clone of Bpifa1 (Myc-DDK-tagged) - Mouse palate, lung, and nasal epithelium associated (Plunc) |
CNY 4750.00 |
|
| MR203753L4 | Lenti ORF clone of Bpifa1 (mGFP-tagged) - Mouse palate, lung, and nasal epithelium associated (Plunc) |
CNY 4750.00 |
