Pvrl2 (BC046770) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	MPH, nectin-2, Cd112
Vector	PCMV6-Kan/Neo
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >BC046770 GGCGAGGGAAAGCTGGGCCGAACGAACTGATCCGGGGAGCCGTGAGCGGCGGAAGCCGGCCTGGAGCCGG ACACTTCAGACCCCTGACTGCCCTCCCAGCCGATCGGTACACGAAGAGTGGTCCCTAGGCACCCCCTGCC CGGGCCCAGTCCCTCCCCGGGCCCCCCATGGCCCGGGCCGCAGTCCTCCCGCCGTCCAGATTGTCACCGA CGCTGCCGTTGTTGCCGCTGCTACTGCTCCTGCTTCAGGAAACAGGAGCCCAAGATGTGCGGGTACGAGT GCTTCCCGAGGTCCGGGGCCGCTTGGGAGGCACCGTGGAGTTACCGTGCCACCTGCTCCCACCCACGACG GAGCGCGTCTCTCAGGTGACCTGGCAGCGCCTGGATGGCACAGTTGTGGCTGCTTTCCACCCATCCTTCG GAGTGGATTTCCCCAACTCTCAGTTCAGCAAGGACCGTCTGTCCTTTGTCAGAGCGAGACCAGAAACAAA CGCAGACCTGCGGGATGCCACACTGGCCTTCCGGGGACTGAGGGTAGAGGACGAGGGCAATTACACCTGC GAGTTTGCCACGTTTCCCAACGGTACCCGCAGGGGGGTGACCTGGCTCAGAGTCATAGCCCAGCCTGAGA ACCACGCTGAAGCCCAGGAGGTCACAATTGGCCCCCAGTCGGTGGCTGTAGCCCGCTGTGTCTCCACTGG GGGCCGCCCCCCTGCCCGAATCACCTGGATCTCATCTCTGGGTGGAGAGGCCAAAGATACTCAGGAGCCA GGGATACAGGCTGGCACCGTCACTATCATCAGCCGATACTCCTTGGTGCCCGTGGGCCGAGCGGATGGCG TCAAGGTCACGTGTAGAGTGGAACACGAGAGCTTCGAAGAGCCGATCCTGCTGCCAGTGACCCTCTCTGT GCGCTACCCTCCAGAAGTATCCATCTCCGGCTATGATGACAACTGGTACCTTGGCCGCAGTGAGGCCATA CTGACCTGTGATGTACGAAGCAACCCAGAGCCCACAGACTATGACTGGAGCACGACCTCGGGCGTCTTCC CAGCCTCTGCAGTGGCCCAGGGCTCTCAGCTGCTTGTCCACTCTGTGGATCGAATGGTCAACACTACCTT CATCTGTACAGCCACCAACGCTGTGGGGACAGGCCGTGCTGAGCAGGTCATCCTGGTGCGAGAGTCACCC AGCACAGCAGGAGCAGGGGCCACTGGTGGCATCATTGGAGGTATTATCGCTGCCATCATCGCCACCGCAG TGGCTGGCACAGGCATCCTCATCTGCCGACAACAGCGGAAGGAGCAGAGGCTTCAAGCTGCGGATGAGGA AGAAGAACTGGAAGGACCTCCCTCCTATAAACCACCCACCCCGAAGGCCAAGCTGGAGGAACCAGAGATG CCCTCTCAACTCTTCACCTTGGGGGCCTCAGAGCACAGCCCAGTGAAGACGCCATACTTTGATGCTGGTG TCTCTTGTGCTGATCAGGAGATGCCTCGGTATCACGAGCTGCCCACTCTGGAAGAGTGGTCAGGGCCCCT GCTGTTGGGGGCTACAGGCCTGGGACCTTCTCTTCTGGTGCCTCCAGGACCCAATGTTGTGGAGGGGGTT TCCCTGAGTCTCGAAGATGAGGAGGAAGATGATGAGGAGGAAGACTTCCTGGATAAAATCAACCCTATTT ATGATGCCCTGTCCTACCCCAGCCCCTCTGACTCCTACCAGAGCAAAGACTTTTTTGTGTCACGGGCCAT GTATGTGTGAGGGAGGCACAGGGGCTCTGACGTCTCACCTTTCACCCTTGACCCATGAGCTTTCCACCAG TAATCTAGGACACTCTGACTTCCAGGCAGACCAGGGACAACTATCACCCATTGCAATCCACCTGTGACTT CTTAGTGACTCCACCATGACGTCCAATCTATGATGTCTGAGGCAGGCAAACCTGCACAACTGGAAACCTG GAGATTTTTATCTCCCTTGGCAGGGAGCTCACCATATCCTTCTGCACCACCTGTGACCCCCCCCCCCCCC CCAAGGACTCCTAAGACTACGACCCTTTGACCATGCCACTCAGTATCTCAAGAACCCTTAAAGTCCCAAA GGAATCGGACCTTGCACTTGTCCTCAGGCAATAGAGTCCAACAGATATGCAAGAACGGGATCAGGGGCTC CCTGTTGCTCAGACCTGAGCCCTCCAGGCAGCAGAAGCTCACCTGATCCCTCCCCACCCTGCTCCCCAAA GGTGAAAAGGAGAGGATTCCCCAATGTAAGGTAGGACCTCCCCATCTCCACCTACTCCTGCAGGCAGGAA TCTCAGGTTTCTCACACCCTCTCCTCAGCACCCAGGTTCCTGTCTCCAGAGCATGAATTCCAGGTCCAAT GCTAGAGGGGAGAACCTAATGCAAGTGTGCCTTGCCACCCCAAGTTTGGGAGACTCTGCTCTTATCCTGA GGACTACTGAATTCTTTTAACCCCTACCCAGTGAGATGAGAACTACATATCCCTCTTTAGGGGATGGTGT GTGTATGTGTGTGTGATGGAGAATCTGGGCATCTGGGTTGGGAATTTTATTTTGTAAGCATTTCCTACAT AATATGAGTTTCTACTTTGATAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites	AscI-NotI
ACCN	BC046770
Insert Size	1593 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC046770, AAH46770
RefSeq Size	2633 bp
RefSeq ORF	1593 bp
Locus ID	19294
Gene Summary	Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.[UniProtKB/Swiss-Prot Function]

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