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Ppp3ca (NM_008913) Mouse Untagged Clone
CAT＃: MC217435
Ppp3ca (untagged) - Mouse protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca), (10ug)
CNY 6,750.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2900074D19Rik; Caln; Calna; CN; CnA |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC217435 representing NM_008913
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCGAGCCCAAGGCGATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGCCGTTCCATTTC CACCAAGTCACCGGCTGACAGCAAAGGAAGTGTTTGATAATGATGGGAAACCTCGTGTGGATATCTTAAA AGCACATCTCATGAAGGAGGGCAGGCTGGAAGAAAGTGTTGCATTGAGAATAATAACAGAGGGTGCTTCG ATTCTCCGACAGGAAAAAAACTTGCTGGATATCGACGCACCAGTCACAGTTTGTGGGGACATCCATGGAC AATTCTTTGACTTGATGAAGCTCTTTGAAGTGGGAGGATCTCCTGCCAACACTCGCTACCTCTTCTTAGG GGACTATGTTGACAGAGGGTACTTCAGTATCGAATGTGTGCTGTATTTGTGGGCCTTGAAAATTCTTTAC CCCAAAACACTGTTTTTACTTCGCGGAAACCATGAATGTAGGCACCTCACAGAGTATTTCACGTTTAAAC AAGAATGTAAAATAAAGTATTCAGAACGCGTTTATGACGCCTGTATGGATGCCTTCGACTGCCTTCCCCT GGCTGCGCTAATGAACCAGCAGTTCCTGTGTGTACACGGTGGTTTGTCTCCAGAGATTAACACTCTAGAT GACATCAGAAAATTAGACCGATTCAAAGAACCACCTGCTTATGGGCCCATGTGTGACATCCTATGGTCAG ACCCCCTGGAGGACTTTGGAAATGAGAAGACTCAGGAACATTTCACTCACAACACAGTCAGAGGCTGTTC GTACTTCTACAGTTACCCAGCTGTGTGTGACTTCCTGCAGCACAATAATTTGTTGTCCATACTCCGCGCC CACGAAGCCCAGGATGCAGGGTACCGCATGTACAGGAAAAGCCAAACAACAGGCTTCCCGTCTCTAATTA CAATCTTCTCGGCACCAAATTACTTAGATGTGTACAATAACAAAGCTGCAGTGTTGAAGTACGAGAACAA TGTGATGAACATCAGGCAGTTCAACTGCTCCCCGCATCCGTACTGGCTCCCAAATTTCATGGATGTTTTC ACCTGGTCGCTGCCATTTGTTGGGGAGAAAGTGACTGAGATGCTGGTCAATGTTCTCAACATCTGCTCCG ACGATGAACTGGGGTCAGAAGAAGATGGATTTGACGGAGCCACGGCCGCAGCCCGGAAGGAAGTCATCAG AAACAAGATCCGAGCAATAGGCAAAATGGCCAGAGTGTTCTCAGTTCTCAGAGAAGAGAGTGAGAGTGTC CTGACACTGAAGGGCCTGACCCCAACTGGCATGCTCCCCAGCGGAGTGCTCTCTGGCGGGAAACAGACTC TGCAAAGCGCTACTGTTGAGGCTATTGAGGCTGATGAAGCCATCAAAGGATTTTCACCACAACATAAGAT CACTAGCTTCGAGGAGGCCAAGGGCTTAGACCGAATTAACGAGAGGATGCCACCTCGCAGAGACGCCATG CCCTCTGACGCCAACCTTAACTCCATCAACAAGGCTCTCGCCTCAGAGACTAACGGCACGGACAGCAATG GCAGTAATAGCAGCAATATCCAGTGA AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_008913 |
| Insert Size | 1566 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_008913.5, NP_032939.1 |
| RefSeq Size | 4862 bp |
| RefSeq ORF | 1566 bp |
| Locus ID | 19055 |
| UniProt ID | P63328 |
| Gene Summary | Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals (PubMed:7791792, PubMed:26794871). Many of the substrates contain a PxIxIT motif and/or a LxVP motif (By similarity). In response to increased Ca(2+) levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (By similarity). In response to increased Ca(2+) levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (By similarity). Dephosphorylates heat shock protein HSPB1 (By similarity). Dephosphorylates and activates transcription factor NFATC1 (By similarity). Dephosphorylates and inactivates transcription factor ELK1 (By similarity). Dephosphorylates DARPP32 (By similarity). May dephosphorylate CRTC2 at 'Ser-171' resulting in CRTC2 dissociation from 14-3-3 proteins (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227082 | Ppp3ca (tGFP-tagged) - Mouse protein phosphatase 3 catalytic subunit alpha isoform (Ppp3ca), (10ug) |
CNY 5,800.00 |
|
| MR227082 | Ppp3ca (Myc-DDK-tagged) - Mouse protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca) |
CNY 5,816.00 |
|
| MR227082L3 | Lenti ORF clone of Ppp3ca (Myc-DDK-tagged) - Mouse protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca) |
CNY 7,130.00 |
|
| MR227082L4 | Lenti ORF clone of Ppp3ca (mGFP-tagged) - Mouse protein phosphatase 3, catalytic subunit, alpha isoform (Ppp3ca) |
CNY 7,130.00 |
