Socs5 (NM_019654) Mouse Untagged Clone
CAT＃: MC217592
Socs5 (untagged) - Mouse suppressor of cytokine signaling 5 (Socs5), (10ug)
CNY 6840.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1810018L08Rik; Cish5; mKIAA0671 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC217592 representing NM_019654
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATAAAGTGGGGAAAATGTGGAACAACTTAAAATACAGATGCCAGAATCTCTTCAGCCACGAGGGAG GAAGCCGTAATGAGAACGTGGAGATGAACCCCAACAGATGTCCGTCTGTCAAAGAGAAAAGCATCAGTCT GGGAGAGGCAGCTCCCCAGCAAGAGAGCAGTCCCTTAAGAGAAAATGTTGCCTTACAGCTGGGACTGAGC CCTTCCAAGACCTTTTCCAGGCGGAACCAAAACTGTGCCGCAGAGATCCCTCAAGTGGTTGAAATCAGCA TCGAGAAAGACAGTGACTCGGGTGCCACCCCAGGAACGAGGCTTGCACGGAGAGACTCCTACTCGCGGCA CGCCCCGTGGGGAGGAAAGAAGAAACATTCCTGTTCCACAAAGACCCAGAGTTCATTGGATACCGAGAAA AAGTTTGGTAGAACTCGAAGCGGCCTTCAGAGGCGAGAGCGGCGCTATGGAGTCAGCTCCATGCAGGACA TGGACAGCGTTTCTAGCCGCGCGGTCGGGAGCCGCTCCCTGAGGCAGAGGCTCCAGGACACGGTGGGTTT GTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCACTCTTTTCCAATAAAAGAAAAATACATCTT TCTGAATTAATGCTGGAGAAATGCCCTTTTCCTGCTGGCTCGGATTTAGCACAAAAGTGGCATTTGATTA AACAGCATACCGCCCCTGTGAGCCCACACTCAACATTTTTTGATACATTTGATCCATCACTGGTGTCTAC AGAAGATGAAGAAGATAGGCTTCGCGAGAGAAGACGGCTTAGTATCGAAGAAGGGGTGGATCCCCCTCCC AACGCACAAATACACACCTTTGAAGCTACTGCACAGGTCAACCCATTGTATAAGCTGGGACCAAAGTTAG CTCCTGGGATGACAGAGATAAGTGGAGATGGTTCTGCAATTCCACAAACGAATTGTGACTCAGAAGAGGA TTCAACCACCCTATGTCTGCAGTCACGGAGGCAGAAGCAGCGCCAGGTGTCCGGGGACAGCCACGCGCAC GTTAGCAGACAGGGAGCTTGGAAAGTTCATACGCAGATCGATTACATACACTGCCTCGTGCCAGATTTGC TTCAGATCACAGGGAATCCCTGTTACTGGGGCGTGATGGACCGATACGAGGCCGAAGCCCTTCTAGAAGG GAAACCGGAAGGCACGTTCTTGCTCAGGGACTCTGCACAGGAGGACTACCTCTTCTCTGTGAGCTTCCGC CGCTACAACAGGTCTCTGCACGCCCGGATCGAGCAGTGGAACCACAACTTCAGCTTCGATGCCCATGACC CCTGCGTGTTTCACTCCTCCACTGTCACGGGGCTTCTCGAACACTATAAAGACCCCAGCTCTTGCATGTT TTTTGAACCGTTGCTAACGATATCACTGAATAGAACTTTCCCTTTCAGCCTGCAGTATATCTGCCGCGCA GTGATCTGCAGATGCACTACGTATGATGGGATTGACGGGCTCCCGCTACCGTCGATGTTACAGGATTTTT TAAAAGAGTATCATTATAAACAAAAAGTTAGGGTTCGCTGGTTAGAACGAGAACCAGTCAAAGCAAAGTA A ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_019654 |
| Insert Size | 1611 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_019654.2, NP_062628.2 |
| RefSeq Size | 4460 bp |
| RefSeq ORF | 1611 bp |
| Locus ID | 56468 |
| UniProt ID | O54928 |
| Gene Summary | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiation into the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR208589 | Socs5 (Myc-DDK-tagged) - Mouse suppressor of cytokine signaling 5 (Socs5) |
CNY 4000.00 |
|
| MR208589L3 | Lenti ORF clone of Socs5 (Myc-DDK-tagged) - Mouse suppressor of cytokine signaling 5 (Socs5) |
CNY 6460.00 |
|
| MR208589L4 | Lenti ORF clone of Socs5 (mGFP-tagged) - Mouse suppressor of cytokine signaling 5 (Socs5) |
CNY 6460.00 |
