Gldn (NM_177350) Mouse Untagged Clone
CAT＃: MC218890
Gldn (untagged) - Mouse gliomedin (Gldn), (10ug)
CNY 7030.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Clom; Colm; CRG-L2; Crgl2; Crlg2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC218890 representing NM_177350
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACCCGAGCCGCAGAGCGAGGCCAAGGGGCTACAGGCTGGGGGCTGCGCGGCGCCCTGGTGGCCATAG CGCTGCTGTCCGCACTGAACGCCGCGGGCACCGTGTTCGTGCTGTGCCAGTGGCGGGGGTTAAGCGCGGC GCTACGGGCGCTGGAGGCTCAACGCGGCCGAGAGCAGCGCGAGGACAGCGCCCTACGCGCCTTTCTGGCC GAATTGAGTCGTGCGCCGGGCCGGGTCCCCGAACCATCCCAGGACCCCATGAGCGCAGCGCGCAACAAGC GCAGCCACAACGGCGAGCCTGCGTCACACATCCGTGCGGAGAGCCAGGACATGATGATGATGATGACCTA CTCCATGGTGCCGATTCGAGTGATGATAGACCTGTGCAACAGTACCCAGGGCATCTGCCTCACAGGACCA CCGGGCCCACCAGGACCTCCAGGAGCCGGCGGGTTACCAGGCCACAATGGATCAGATGGACAGCCTGGTC TCCAGGGCCCAAAAGGAGAAAAAGGAGCAATTGGCAAGAGAGGAAAAATGGGGTTACCTGGAGCCACCGG AAATCCAGGGGAAAAGGGAGAAAAGGGAGATGCTGGTGAACTGGGTCTACCTGGAAATGAGGGCCCACCA GGGCAGAAAGGTGACAAGGGAGACAAAGGAGACGTGTCCAATGACGTGCTTTTGACAGGTGCCAAAGGTG ACCAAGGTCCCCCTGGCCCCCCTGGACCTCCAGGGCCTCCAGGCCCTCCTGGAAGCAGAAGATCCAAAGG CCCTCGGCCACCAAACGTGTTCAACAGCCAGTGTCCAGGGGAGACGTGTGTCATACCCAATGATGATACC TTGGTGGGAAGAGCTGATGAGAAAGCAAATGAACGCCATTCACCACAAACAGAATCTATGATCACTTCCA TTGGCAACCCAGCCCAAGTCCTAAAAGTGAGAGAGACTTTTGGGACTTGGATGAGAGAGTCTGCTAACAA AAGTGACGACCGCATTTGGGTGACTGAACATTTTTCAGGCATCATGGTGAAGGAGTTCAAAGACCTGCCG GCGCTCCTCAATAGCAGCTTCACCCTCCTCCACCTCCCACATTATTTCCACGGCTGTGGGCACGCTGTTT ACAACAACTCTCTCTACTACCACAAAGGAGGCTCCAACACCATAGTGAGATTTGAATTTGGGAAAGAGAC ACCTCAGACTCTGAAGCTGGAAAATGCTTTGTATTTTGATCGAAAATACCTCTTTGCAAATTCCAAGACT TACTTCAACATAGCAGTGGATGAGAAGGGCATCTGGATTATCTACGCTTCAAGTGTGGATGGCTCAAGCA TCCTTGTAGCACAGCTGGATGAGAGGACATTCTCCGTGACACAGCACATCAACACCACATACCCCAAATC CAAGGCTGGCAATGCCTTCATAGCCCGAGGGATCCTCTATGTCACAGACACCAAAGATACGAGGGTCACG TTTGCCTTTGATTTGTTAGGAGGAAAGCAAATCAATGCAAACTTTGATTTCAGAATGTCCCAGTCTGTTC TTGCCATGCTGTCATACAACATGAGAGATCAGCATTTATACTCGTGGGAAGATGGCCATCTGATGCTCTA TCCTGTGCAGTTTCTGTCAGCGGCATCAAGTCAGCGGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_177350 |
| Insert Size | 1650 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_177350.5, NP_796324.1 |
| RefSeq Size | 4649 bp |
| RefSeq ORF | 1650 bp |
| Locus ID | 235379 |
| UniProt ID | Q8BMF8 |
| Gene Summary | Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC (PubMed:20188654). Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters (PubMed:20188654). Required, together with NRCAM, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier (PubMed:24719088).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG224196 | Gldn (tGFP-tagged) - Mouse gliomedin (Gldn), (10ug) |
CNY 5230.00 |
|
| MR224196 | Gldn (Myc-DDK-tagged) - Mouse gliomedin (Gldn) |
CNY 4088.00 |
|
| MR224196L3 | Lenti ORF clone of Gldn (Myc-DDK-tagged) - Mouse gliomedin (Gldn) |
CNY 6650.00 |
|
| MR224196L4 | Lenti ORF clone of Gldn (mGFP-tagged) - Mouse gliomedin (Gldn) |
CNY 6650.00 |
