Itgb6 (NM_001159564) Mouse Untagged Clone
CAT＃: MC220691
Itgb6 (untagged) - Mouse integrin beta 6 (Itgb6), transcript variant 1, (10ug)
CNY 9120.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2210409C20Rik; 4831415H04Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC220691 representing NM_001159564
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGATTGAGCTGGTCTGCCTGTTTCTGCTACTTCTAGGAAGGAATGATCACGTCCAAGGTGGCTGTG CCTGGGGTGGTGCAGAAAGCTGCTCAGACTGCCTGCTCACAGGACCCCACTGCGCCTGGTGCTCCCAGGA GAATTTCACCCACCTGTCTGGAGCTGGCGAGAGGTGCGACACCCCAGCGAATCTTTTAGCCAAAGGATGT CAACTACCCTTCATTGAAAACCCTGTCTCCCGCATAGAAGTCCTTCAAAATAAGCCTCTCAGCGTGGGCC GACAGAAGAACAGTTCTGACATTGTTCAGATTGCTCCTCAAAGCTTGGTTCTTAAATTGAGACCAGGGCG TGAGCAGACTCTGCAAGTGCAGGTCCGCCAAACTGAAGATTACCCAGTAGATCTGTATTACCTCATGGAC CTCTCCGCCTCTATGGATGACGACCTCAACACCATCAAAGAGCTTGGCTCCCGGCTGGCCAAAGAGATGT CCAAACTAACCAGCAACTTTAGACTGGGCTTTGGCTCTTTTGTGGAAAAGCCCGTTTCTCCTTTTATGAA AACAACCCCAGAGGAAATCACCAACCCTTGCAGTAGTATCCCCTATTTCTGCTTACCTACATTTGGATTC AAGCACATTTTGCCATTAACTGATGATGCCGAGAGATTCAATGAAATTGTGAGGAAACAGAAGATTTCTG CTAATATTGACACACCTGAAGGTGGATTTGATGCAATCATGCAGGCTGCTGTGTGTAAGGAAAAGATTGG CTGGCGCAATGACTCGCTCCACCTCCTGGTTTTTGTGAGTGATGCCGATTCTCATTTTGGAATGGACAGC AAGCTGGCAGGCATTGTCATTCCCAATGATGGACTCTGTCACTTGGACCACAGGAATGAATATTCCATGT CAACTGTCTTGGAATATCCAACTATCGGCCAACTCATTGATAAACTGGTACAAAACAACGTGCTACTGAT CTTTGCAGTCACCCAAGAACAAGTCCATCTGTATGAGAACTATGCAAAACTCATTCCTGGAGCAACCGTG GGACTGCTTCAGAAGGATTCTGGGAACATCCTTCAGCTGATCATCTCCGCTTATGAAGAACTGCGGTCTG AGGTGGAACTGGAAGTGTTAGGGGACACAGAAGGACTCAACCTGTCTTTCACAGCTCTCTGTAACAATGG TGTCCTCTTCCCACACCAAAAGAAATGCTCCCACATGAAAGTTGGAGACACAGCATCCTTCAATGTGACT GTGAGCGTATCCAACTGTGAGAAAAGAAGCAGGAACCTCATCATAAAGCCAGTGGGGCTGGGGGACACCC TAGAAATACTCGTCAGTGCAGAATGTGACTGCGACTGCCAGAGAGAAATAGAAACTAACAGCTCTAAGTG TCACAATGGGAATGGCTCCTTCCAGTGTGGGGTGTGTACCTGCAACCCCGGCCACATGGGTCCTCACTGC GAGTGTGGTGAGGATATGGTGAGCACGGATTCCTGCAAGGAGTCCCCGGGTCACCCTTCATGCAGTGGAA GGGGTGACTGCTATTGTGGGCAGTGCATCTGCCACTTATCGCCGTACGGAAGCATCTACGGACCTTACTG CCAGTGTGACAACTTCTCCTGTCTGAGACACAAAGGCCTTCTCTGTGGAGATAACGGTGACTGTGACTGT GGCGAGTGTGTGTGCCGGGATGGCTGGACAGGTGAATACTGTAACTGTACAACCAACAGGGACTCGTGTA CATCTGAGGATGGAGTGCTGTGCAGTGGACGTGGGGACTGTGTCTGTGGCAAGTGTGTCTGCAGAAACCC TGGAGCCTCAGGACCCACCTGTGAACGCTGTCCTACCTGTGGCGACCCCTGTAACTCTAAACGGAGTTGC ATCGAGTGCTACCTGTCTGCAGATGGCCAGGCCCAAGAAGAGTGTGCTGACAAGTGTAAAGCCATTGGTG CCACCATCAGTGAGGAAGATTTTTCAAAGGATACTTCTGTCTCCTGCTCTCTACAAGGAGAAAATGAATG CCTTATTACATTCCTAATAACTACGGATAATGAAGGGAAAACCATCATTCACAACATCAATGAAAAAGAC TGCCCCAAACCTCCAAACATTCCCATGATCATGTTGGGGGTGTCACTGGCGATCCTGCTCATCGGAGTTG TGCTACTGTGCATTTGGAAGCTGCTGGTATCATTTCATGACCGGAAGGAAGTTGCTAAATTTGAAGCAGA ACGCTCTAAGGCCAAGTGGCAAACGGGAACCAATCCTCTGTACCGAGGTTCCACCAGCACTTTTAAGAAC GTGACCTACAAGCACAGGGAGAAGCACAAAGCAGGCCTTTCCTCAGATGGGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001159564 |
| Insert Size | 2364 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001159564.1, NP_001153036.1 |
| RefSeq Size | 4894 bp |
| RefSeq ORF | 2364 bp |
| Locus ID | 16420 |
| UniProt ID | Q9Z0T9 |
| Gene Summary | Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (PubMed:10025398). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:10025398).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR210654 | Itgb6 (Myc-DDK-tagged) - Mouse integrin beta 6 (Itgb6), transcript variant 1 |
CNY 8648.00 |
|
| MR210654L1 | Lenti ORF clone of Itgb6 (Myc-DDK-tagged) - Mouse integrin beta 6 (Itgb6), transcript variant 1 |
CNY 7700.00 |
|
| MR210654L2 | Lenti ORF clone of Itgb6 (mGFP-tagged) - Mouse integrin beta 6 (Itgb6), transcript variant 1 |
CNY 11048.00 |
|
| MR210654L3 | Lenti ORF clone of Itgb6 (Myc-DDK-tagged) - Mouse integrin beta 6 (Itgb6), transcript variant 1 |
CNY 7700.00 |
|
| MR210654L4 | Lenti ORF clone of Itgb6 (mGFP-tagged) - Mouse integrin beta 6 (Itgb6), transcript variant 1 |
CNY 7700.00 |
