Pak7 (NM_172858) Mouse Untagged Clone
CAT＃: MC221051
Pak7 (untagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7), (10ug)
CNY 9220.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2900083L08Rik; 6430627N20; PAK-5; PAK-7; Pak5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221051 representing NM_172858
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTTTGGGAAGAAAAAGAAAAAGATCGAAATATCTGGCCCATCCAACTTTGAACACAGGGTTCATACTG GATTTGATCCACAAGAGCAGAAGTTTACTGGCCTTCCCCAGCAGTGGCACAGCCTGTTAGCAGACACAGC CAACAGGCCCAAGCCCATGGTGGACCCATCATGCATCACACCCATACAGCTGGCTCCCATGAAGACAATC GTCAGAGGAAATAAATCCTGCAAGGAAACCTCTATCAATGGTCTGCTAGAGGATTTTGACAACATCTCCG TGACTCGCTCCAACTCTCTAAGGAAAGAAAGCCCACCCACCCCAGATCAGGGAGCAGCTAGCCGCATTCA AGGCCACTCGGAAGAGAACGGCTTCATCACTTTCTCACAATATTCCAGTGAATCCGATACGACTGCGGAC TACACAACTGAAAAGTACAGAGACAGGAGTCTCTATGGAGATGACCTGGATCTGTACTATAAAAGCAGCC ATGCAGCCAAGCAAAATGGGCATGCCATGAAGATGAAACATGGAGACGCTTACTACCCTGAGATGAAGTC TTTGAAAACCGACCTGGCCGGATTCCCTGTCGACTATCACACCCACTTGGACTCTCTGAGAAAATCAAGT GAATATGGTGACCTTAGGTGGGATTATCAGAGAGCCTCTAGTAGCTCCCCTCTGGACTACTCATTCCAGC TCACGCCTTCTAGAACTGCAGGGACCAGCAGGTGCTCCAAGGAGAGTCTGGCATACAGTGAAAGTGATTG GGGACCCAGCCTGGATGACTATGACAGGAGGCCAAAATCATCATACCTGCATCAGACGAGCCCTCAGCCA GCCATGCGCCAGAGATCCAAGTCCGGCTCAGGGCTTCAGGAACCCATGATGCCATTTGGAGCAAGTGCAT TTAAAACTCATCCTCAAGGACACTCGTACAACTCCTACACCTACCCTCGATTGTCCGAGCCCACAATGTG CATTCCAAAGGTGGATTACGATCGAGCACAGATGGTCTTCAGTCCTCCACTGTCAGGGTCCGACACTTAC CCCAGAGGCCCCACCAAACTACCTCAAAGTCAAAGCAAAGCAGGCTACTCTTCAGGCAGCCACCAGTACC CTTCTGGGTACCACAAAGCATCTCTATACCACCATCCATCCCTGCAAACCAGTTCTCAGTACATCTCCAC CGCTTCTTACTTAAGCTCTCTCAGTATCTCCTCGAGCACCTACCCTCCACCTAGCTGGGGCTCCTCCTCA GACCAGCAGCCCTCAAGGGTATCCCATGAACAATTCCGAGCTGCCCTGCAACTGGTGGTCAGCCCAGGAG ACCCCAGGGAATATTTGGATAACTTTATTAAAATCGGAGAAGGGTCGACAGGCATCGTGTGCATTGCAAC AGAGAAACACACAGGCAAGCAAGTGGCAGTGAAGAAAATGGACCTCCGAAAGCAGCAGAGACGGGAACTC CTTTTTAATGAGGTCGTGATAATGCGTGATTACCACCATGACAACGTAGTTGACATGTACAACAGCTACC TTGTTGGAGATGAGCTCTGGGTGGTCATGGAGTTTCTAGAAGGTGGTGCCTTGACAGACATTGTCACTCA TACCAGAATGAATGAAGAGCAGATAGCTACTGTCTGCCTGTCAGTTCTGAAAGCTCTGTCCTACCTTCAT AACCAAGGAGTGATTCACAGGGACATAAAGAGTGACTCCATTCTTCTGACAAGCGATGGCCGGATAAAGT TATCTGACTTTGGTTTCTGTGCTCAAGTTTCCAAAGAGGTGCCAAAGAGGAAGTCACTGGTGGGTACCCC ATACTGGATGGCACCTGAGGTGATTTCCAGGCTACCTTATGGGACAGAGGTGGACATCTGGTCCCTCGGG ATAATGGTGATAGAGATGATTGATGGGGAGCCCCCCTATTTCAATGAGCCTCCTCTGCAGGCCATGAGGA GGATCCGGGACAGTTTACCTCCAAGAGTGAAGGACCTACACAAGGTTTCTTCCATGCTCCGAGGATTCCT AGATCTTATGTTGGTGAGGGAGCCCTCTCAAAGAGCCACAGCTCAAGAACTCCTTGGACATCCATTCTTA AAATTGGCAGGTCCACCATCTTGCATTGTTCCTCTCATGAGACAATACAGACATCACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_172858 |
| Insert Size | 2160 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_172858.2, NP_766446.2 |
| RefSeq Size | 4773 bp |
| RefSeq ORF | 2160 bp |
| Locus ID | 241656 |
| UniProt ID | Q8C015 |
| Gene Summary | Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 through 3 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG218929 | Pak7 (tGFP-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7), (10ug) |
CNY 6370.00 |
|
| MR218929 | Pak7 (Myc-DDK-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) |
CNY 5264.00 |
|
| MR218929L3 | Lenti ORF clone of Pak7 (Myc-DDK-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) |
CNY 7700.00 |
|
| MR218929L4 | Lenti ORF clone of Pak7 (mGFP-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) |
CNY 7700.00 |
